Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4848203 | 1.00 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1TDP1CASP3 | |
| SCHEMBL669399 | 0.87 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1TDP1CASP3 | |
| SCHEMBL2432527 | 0.87 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1TDP1CASP3 | |
| SCHEMBL14291140 | 0.83 | ALDH1A1 (0.39) | ALDH1A1KDM4EHTT | |
| SCHEMBL2434266 | 0.82 | KMT2A (0.36) | ALDH1A1KMT2AMEN1TDP1CASP3 | |
| SCHEMBL2434263 | 0.82 | KMT2A (0.36) | ALDH1A1KMT2AMEN1TDP1CASP3 | |
| SCHEMBL2431591 | 0.80 | KMT2A (0.37) | ALDH1A1KMT2AMEN1TDP1CASP3 | |
| SCHEMBL2431589 | 0.80 | KMT2A (0.37) | ALDH1A1KMT2AMEN1TDP1CASP3 | |
| SCHEMBL14290921 | 0.78 | KMT2A (0.41) | ALDH1A1KMT2AMEN1TDP1CASP3 | |
| SCHEMBL4756918 | 0.78 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1TDP1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008017688-A1 | 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-14 | — | — | WO | disclosed |