Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | CCR2 | P41597 | 17/20 | 0.64 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.54 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13271425 | 0.83 | CCR2 (0.77) | CCR2 | |
| SCHEMBL7803789 | 0.83 | KDM4E (0.69) | KDM4EPKMTGFBR1RORC | |
| SCHEMBL612690 | 0.82 | CCR2 (0.63) | CCR2 | |
| SCHEMBL4848232 | 0.82 | CCR2 (0.49) | KDM4EPKMCCR2TGFBR1 | |
| SCHEMBL21586161 | 0.79 | KDM4E (0.76) | KDM4EPKMTGFBR1 | |
| SCHEMBL4841386 | 0.79 | CCR2 (0.65) | CCR2 | |
| SCHEMBL311246 | 0.79 | STS (0.56) | KDM4EPKMTGFBR1 | |
| SCHEMBL4874671 | 0.79 | CCR2 (0.59) | CCR2 | |
| SCHEMBL3745349 | 0.79 | CCR2 (0.59) | CCR2 | |
| SCHEMBL765370 | 0.79 | CCR2 (0.59) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100418951-C | Cycloamine derivative and its use as medicine | TEIJIN KASEI LTD (JP) | 2008-09-17 | — | — | CN | disclosed |
| US-7390830-B1 | Remedies or prophylactics for diseases in association with chemokines | TEIJIN LIMITED (JP) | 2008-06-24 | — | — | US | disclosed |
| CN-1240699-C | Therapeutic or prophylactic agent for chemokine-associated diseases | TEIJIN LTD (JP) | 2006-02-08 | — | — | CN | disclosed |
| EP-1179341-B1 | REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES | TEIJIN LTD (JP) | 2005-11-09 | — | — | EP | disclosed |
| CN-1660815-A | Cyclic amine derivatives and their use as drugs | TEIJIN LTD (JP) | 2005-08-31 | — | — | CN | disclosed |
| EP-1553085-A1 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-07-13 | — | — | EP | disclosed |
| EP-1535909-A2 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-06-01 | — | — | EP | disclosed |
| CN-1496981-A | Cyclic amine derivatives and their use as pharmaceuticals | ������������ʽ���� | 2004-05-19 | — | — | CN | disclosed |
| CN-1384743-A | Remedies or preventives for diseases in association with chemokines | TEIJIN LTD (JP) | 2002-12-11 | — | — | CN | disclosed |
| US-6451842-B1 | Cyclic amine derivatives and their use as drugs | DUPONT PHARMACEUTICALS COMPANY | 2002-09-17 | — | — | US | disclosed |
| US-6410566-B1 | ATHEROSCLEROSIS; ANTIARTHRITIC AGENTS | TEIJIN LIMITED (JP) | 2002-06-25 | — | — | US | disclosed |
| US-6362177-B1 | INHIBITION OF CHEMOKINE BINDING | TEIJIN LIMITED (JP) | 2002-03-26 | — | — | US | disclosed |
| EP-1179341-A1 | REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES | TEIJIN LIMITED (JP) | 2002-02-13 | — | — | EP | disclosed |
| CN-1279668-A | Cyclic amine derivatives and their use as pharmaceuticals | TEIJIN LTD (JP) | 2001-01-10 | — | — | CN | disclosed |