Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CCR2 | P41597 | 3/20 | 0.53 |
| ▸ | BCHE | P06276 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.49 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4840961 | 0.93 | TP53 (0.62) | GAATP53CCR2BCHEFAAH | |
| SCHEMBL4848447 | 0.85 | CCR2 (0.66) | TP53CCR2BCHEFAAHACHE | |
| Hydrochloric Acid SCHEMBL4847979 | 0.84 | CCR2 (0.65) | TP53CCR2BCHEFAAHACHE | |
| SCHEMBL4848703 | 0.82 | CCR2 (0.79) | LTA4HCCR2BCHEKMT2AMEN1 | |
| SCHEMBL4854395 | 0.79 | GAA (0.59) | GAALTA4HTP53BCHEKMT2A | |
| SCHEMBL6267504 | 0.76 | CYP2D6 (0.72) | GAALTA4HKMT2ANPC1 | |
| SCHEMBL1543281 | 0.76 | BCHE (0.68) | GAABCHEKMT2AMEN1ACHE | |
| SCHEMBL4578600 | 0.76 | CHRM5 (0.54) | LTA4HCCR3POLB | |
| SCHEMBL3614165 | 0.76 | CCR3 (0.50) | KMT2AMEN1FAAHCCR3POLB | |
| SCHEMBL27579145 | 0.76 | LTA4H (0.52) | GAALTA4HTP53BCHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7390830-B1 | Remedies or prophylactics for diseases in association with chemokines | TEIJIN LIMITED (JP) | 2008-06-24 | — | — | US | disclosed |
| EP-1179341-B1 | REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES | TEIJIN LTD (JP) | 2005-11-09 | — | — | EP | disclosed |