Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | BAX | Q07812 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ESRRA | P11474 | 1/20 | 0.32 |
| ▸ | BRS3 | P32247 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4810958 | 0.74 | KIF11 (0.43) | KIF11ADAMTS5LTA4HSCN9AALDH1A1 | |
| SCHEMBL9589615 | 0.61 | LTA4H (0.53) | NR1H2KIF11LTA4HBAXALDH1A1 | |
| SCHEMBL4043144 | 0.61 | LTA4H (0.53) | NR1H2KIF11LTA4HBAXALDH1A1 | |
| SCHEMBL9589071 | 0.60 | LTA4H (0.52) | NR1H2KIF11LTA4HBAXALDH1A1 | |
| SCHEMBL9588710 | 0.60 | LTA4H (0.82) | NR1H2LTA4HBAXALDH1A1GAA | |
| SCHEMBL249608 | 0.60 | LTA4H (0.73) | NR1H2LTA4HBAXALDH1A1GAA | |
| SCHEMBL3167834 | 0.60 | LTA4H (0.73) | NR1H2LTA4HBAXALDH1A1GAA | |
| SCHEMBL4308678 | 0.60 | LTA4H (0.51) | NR1H2LTA4HBAXGAA | |
| SCHEMBL8632090 | 0.59 | AR (0.47) | NR1H2NR1H3PDK2LTA4HBAX | |
| SCHEMBL9588167 | 0.59 | LTA4H (0.53) | NR1H2LTA4HBAXSCN9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | disclosed |