Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4848663 | 1.00 | EPHX1 (0.40) | EPHX1CTSSCTSKBTKGAA | |
| SCHEMBL16469900 | 0.98 | EPHX1 (0.43) | EPHX1CTSSCTSKBTKGAA | |
| SCHEMBL490642 | 0.88 | CTSS (0.41) | EPHX1CTSSCTSKBTKGAA | |
| SCHEMBL1147463 | 0.88 | CTSS (0.41) | EPHX1CTSSCTSKBTKGAA | |
| SCHEMBL16470240 | 0.85 | EPHX1 (0.42) | EPHX1CTSSCTSKBTKGAA | |
| SCHEMBL27757442 | 0.84 | CTSS (0.40) | EPHX1CTSSCTSKBTKGAA | |
| SCHEMBL376033 | 0.84 | CTSS (0.40) | EPHX1CTSSCTSKBTKGAA | |
| SCHEMBL375865 | 0.84 | CTSS (0.40) | EPHX1CTSSCTSKBTKGAA | |
| SCHEMBL375738 | 0.84 | EPHX1 (0.38) | EPHX1CTSSCTSKBTKGAA | |
| SCHEMBL490856 | 0.83 | CTSK (0.39) | EPHX1CTSSCTSKBTKGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053157-A1 | AMINOHETEROARYL COMPOUNDS AS FOR THE TREATMENT OF DISEASES MEDIATED BY C-MET KINASE ACTIVITY | CHROMA THERAPEUTICS LTD. (GB) | 2008-05-08 | — | — | WO | disclosed |