Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 17/20 | 0.47 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.35 |
| ▸ | SKP1 | P63208 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785845 | 0.90 | HRH4 (0.44) | PIK3CAMTORPIK3R1 | |
| SCHEMBL4846093 | 0.90 | HRH4 (0.44) | PIK3CAMTORPIK3R1 | |
| SCHEMBL4783926 | 0.90 | HRH4 (0.44) | PIK3CAMTORPIK3R1 | |
| SCHEMBL4782301 | 0.88 | PIK3CA (0.43) | PIK3CAMTORPIK3R1PIK3CBPIK3CG | |
| SCHEMBL4784653 | 0.86 | ADORA3 (0.43) | PIK3CAMTORPIK3CG | |
| SCHEMBL4781396 | 0.86 | PIK3CA (0.41) | PIK3CAMTORPIK3R1ALDH1A1HPGD | |
| SCHEMBL4782797 | 0.86 | PIK3CA (0.42) | PIK3CAMTORPIK3R1ALDH1A1MAPT | |
| SCHEMBL4784093 | 0.86 | PIK3CA (0.43) | PIK3CAMTORPIK3R1ALDH1A1HPGD | |
| SCHEMBL4784017 | 0.85 | HTR2A (0.44) | PIK3CAMTORALDH1A1MAPTTSHR | |
| SCHEMBL14161649 | 0.85 | PIK3CA (0.41) | PIK3CAMTORPIK3R1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | claimed |