Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7280790 | 0.83 | CYP2C9 (0.53) | CYP2C9HIF1AKMT2AMEN1ATM | |
| SCHEMBL7280783 | 0.83 | CYP2C9 (0.53) | CYP2C9HIF1AKMT2AMEN1ATM | |
| SCHEMBL8851729 | 0.75 | SLC2A1 (0.49) | CYP2C9HIF1AKMT2AMEN1ATM | |
| SCHEMBL4853510 | 0.74 | CDC25B (0.56) | CYP2C9HIF1AKMT2AHPGDSCDC25B | |
| SCHEMBL1428333 | 0.73 | CYP2C9 (0.58) | CYP2C9HIF1AKMT2AMEN1ATM | |
| SCHEMBL8429646 | 0.72 | CYP2C9 (0.57) | CYP2C9HIF1AKMT2AMEN1ATM | |
| SCHEMBL2608801 | 0.72 | CYP2C9 (0.57) | CYP2C9HIF1AKMT2AMEN1ATM | |
| SCHEMBL10871252 | 0.72 | CYP2C9 (0.57) | CYP2C9HIF1AKMT2AMEN1ATM | |
| SCHEMBL15802462 | 0.72 | SLC2A1 (0.58) | CYP2C9HIF1AKMT2AMEN1ATM | |
| SCHEMBL1599374 | 0.71 | CYP2C9 (0.56) | CYP2C9HIF1AKMT2AMEN1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7459555-B2 | Photochromic naphthopyrans | RODENSTOCK GMBH (DE) | 2008-12-02 | — | — | US | disclosed |
| US-20020052499-A1 | Photochromic naphthopyrans | OPTISCHE WERKE G. RODENSTOCK | 2002-05-02 | — | — | US | disclosed |
| US-6342459-B1 | PHOTOCHROMIC COMPOUNDS AND ARTICLES OF RESIN FOR OPTHTHALMIC LENSES | OPTISCHE WERKE G. RODENSTOCK (DE) | 2002-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052499-A1 | Photochromic naphthopyrans | BPNT1, NR2E3, BRIX1 | CYP2C9 1502/4885HIF1A 1807/4885KMT2A 3126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.