Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 2/20 | 0.56 |
| ▸ | PLK1 | P53350 | 1/20 | 0.55 |
| ▸ | HPGDS | O60760 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | STAT6 | P42226 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4469856 | 0.79 | CDC25B (0.78) | CDC25BPLK1HPGDSMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL11445757 | 0.77 | CDC25B (0.76) | CDC25BPLK1HPGDSMAPTKMT2A | |
| SCHEMBL14124722 | 0.76 | CDC25B (0.64) | CDC25BPLK1HPGDSMAPTKMT2A | |
| SCHEMBL7842295 | 0.75 | PLK1 (0.67) | CDC25BPLK1HPGDSMAPTKMT2A | |
| SCHEMBL4518755 | 0.75 | PLK1 (0.67) | CDC25BPLK1HPGDSMAPTKMT2A | |
| SCHEMBL10975672 | 0.74 | HPGDS (0.59) | CDC25BPLK1HPGDSMAPTKMT2A | |
| SCHEMBL10975665 | 0.74 | HPGDS (0.59) | CDC25BPLK1HPGDSMAPTKMT2A | |
| Cyanide SCHEMBL11198616 | 0.74 | CDC25B (0.71) | CDC25BPLK1HPGDSMAPTKMT2A | |
| SCHEMBL6250609 | 0.74 | MAPT (0.77) | CDC25BPLK1HPGDSMAPTKMT2A | |
| SCHEMBL7560388 | 0.74 | CDC25B (0.88) | CDC25BPLK1HPGDSMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7459555-B2 | Photochromic naphthopyrans | RODENSTOCK GMBH (DE) | 2008-12-02 | — | — | US | disclosed |
| US-20020052499-A1 | Photochromic naphthopyrans | OPTISCHE WERKE G. RODENSTOCK | 2002-05-02 | — | — | US | disclosed |
| EP-1005464-B1 | PHOTOCHROMIC NAPHTHOPYRANS | RODENSTOCK OPTIK G (DE) | 2002-04-17 | — | — | EP | disclosed |
| US-6342459-B1 | PHOTOCHROMIC COMPOUNDS AND ARTICLES OF RESIN FOR OPTHTHALMIC LENSES | OPTISCHE WERKE G. RODENSTOCK (DE) | 2002-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052499-A1 | Photochromic naphthopyrans | BPNT1, NR2E3, BRIX1 | CDC25B 1513/4885PLK1 4427/4885HPGDS 1279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.