Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.68 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5052007 | 0.85 | NAPRT (0.72) | NAPRTALDH1A1RAB9ANPC1TSHR | |
| SCHEMBL23907015 | 0.82 | NAPRT (0.64) | NAPRTALDH1A1RAB9ANPC1KMT2A | |
| SCHEMBL11005335 | 0.81 | NAPRT (0.68) | NAPRTBCHEALDH1A1RAB9ANPC1 | |
| SCHEMBL4322796 | 0.81 | NAPRT (0.68) | NAPRTALDH1A1RAB9AMAPTKMT2A | |
| SCHEMBL3531406 | 0.81 | NAPRT (0.68) | NAPRTRAB9ATSHRKMT2AKDM4E | |
| Antipyrine SCHEMBL28245052 | 0.81 | NAPRT (0.93) | NAPRTBCHEPTGS2ALDH1A1RAB9A | |
| Antipyrine SCHEMBL20452 | 0.81 | NAPRT (1.00) | NAPRTBCHEPTGS2ALDH1A1TSHR | |
| Antipyrine SCHEMBL28311969 | 0.80 | NAPRT (0.89) | NAPRTBCHEPTGS2ALDH1A1RAB9A | |
| Antipyrine SCHEMBL8736656 | 0.79 | NAPRT (0.96) | NAPRTBCHEPTGS2ALDH1A1TSHR | |
| Antipyrine SCHEMBL8995343 | 0.79 | NAPRT (0.96) | NAPRTBCHEPTGS2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7374902-B2 | Enzyme cycling based assays for alpha-methylacyl-CoA racemase | GENERAL ATOMICS (US) | 2008-05-20 | — | — | US | disclosed |
| US-7374897-B2 | Enzyme cycling based assays for alpha-methylacyl-CoA racemase | GENERAL ATOMICS (US) | 2008-05-20 | — | — | US | disclosed |
| US-20060084132-A1 | Enzyme cycling based assays for alpha-methylacyl-CoA racemase | GENERAL ATOMICS | 2006-04-20 | — | — | US | disclosed |
| US-20060084133-A1 | Enzyme cycling based assays for alpha-methylacyl-CoA racemase | GENERAL ATOMICS | 2006-04-20 | — | — | US | disclosed |