SCHEMBL5052007

SCHEMBL5052007

Cc1ccc(-n2c(=O)cc(C)n2C)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 1/20 0.72
ELANE P08246 2/20 0.43
F2 P00734 1/20 0.43
CTSG P08311 1/20 0.43
CMA1 P23946 1/20 0.43
CTRC Q99895 1/20 0.43
MGLL Q99685 1/20 0.41
ALDH1A1 P00352 5/20 0.39
KMT2A Q03164 3/20 0.39
TSHR P16473 2/20 0.39
MEN1 O00255 2/20 0.39
PABPC1 P11940 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
GSK3A P49840 1/20 0.38
GSK3B P49841 1/20 0.38
RGS4 P49798 1/20 0.38
RGS8 P57771 1/20 0.38
LMNA P02545 2/20 0.37
HSD11B1 P28845 1/20 0.36
NOTUM Q6P988 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Antipyrine SCHEMBL27830473 0.87 NAPRT (0.89) NAPRTALDH1A1KMT2ATSHRSMN1; SMN2
SCHEMBL11049152 0.85 NAPRT (0.68) NAPRTMGLLALDH1A1KMT2ATSHR
SCHEMBL4322796 0.85 NAPRT (0.68) NAPRTELANEMGLLALDH1A1KMT2A
SCHEMBL3531406 0.85 NAPRT (0.68) NAPRTMGLLKMT2ATSHRMEN1
SCHEMBL4849110 0.85 NAPRT (0.68) NAPRTALDH1A1KMT2ATSHRMEN1
SCHEMBL11005335 0.85 NAPRT (0.68) NAPRTMGLLALDH1A1KMT2ATSHR
Antipyrine SCHEMBL20452 0.84 NAPRT (1.00) NAPRTALDH1A1KMT2ATSHRSMN1; SMN2
Antipyrine SCHEMBL8995343 0.82 NAPRT (0.96) NAPRTALDH1A1KMT2ATSHRSMN1; SMN2
Antipyrine SCHEMBL8736656 0.82 NAPRT (0.96) NAPRTALDH1A1KMT2ATSHRSMN1; SMN2
Antipyrine SCHEMBL18260589 0.82 NAPRT (0.96) NAPRTALDH1A1KMT2ATSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3892734-B1 SCREENING METHODS AND THERAPEUTIC APPLICATIONS BASED ON BACTERIAL MOTILITY INHIBITION UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) 2024-08-28 EP disclosed
EP-3892734-A1 SCREENING METHODS AND THERAPEUTIC APPLICATIONS BASED ON BACTERIAL MOTILITY INHIBITION Ludwig-Maximilians-Universität München (DE) 2021-10-13 EP disclosed
EP-3892734-A1 SCREENING METHODS AND THERAPEUTIC APPLICATIONS BASED ON BACTERIAL MOTILITY INHIBITION Ludwig-Maximilians-Universität München (DE) 2021-10-13 EP disclosed
US-7345108-B2 Additives for imparting mar and scratch resistance and compositions comprising the same PPG INDUSTRIES OHIO, INC. (US) 2008-03-18 US disclosed
US-7268176-B2 Additives for imparting mar and scratch resistance and compositions comprising the same PPG INDUSTRIES OHIO, INC. (US) 2007-09-11 US disclosed
US-20060178473-A1 Sulfonamide modified aminoplast crosslinkers and powder coating compositions containing such crosslinkers HU SHENGKUI 2006-08-10 US disclosed
US-7087683-B2 Sulfonamide modified aminoplast crosslinkers and powder coating compositions containing such crosslinkers PPG INDUSTRIES OHIO, INC. (US) 2006-08-08 US disclosed
US-20060078748-A1 Novel additives for imparting Mar and scratch resistance and compositions comprising the same AMBROSE RONALD R 2006-04-13 US disclosed
US-6809161-B2 Storage stable PPG INDUSTRIES OHIO, INC. 2004-10-26 US disclosed
US-6797387-B2 UNGELLED REACTION PRODUCT OF AN AMINOPLAST, A URETHANE GROUP-CONTAINING ADDUCT, WHICH IS A PRODUCT OF AN ISOCYANATE AND A POLYFUNCTIONAL POLYMER, AND AROMATIC, KETONE AND 1,4-DIOXANE DERIVATIVES WITH REACTIVE HYDROGEN GROUPS PPG INDUSTRIES OHIO INC. 2004-09-28 US disclosed
WO-2003011932-A1 MODIFIED AMINOPLAST CROSSLINKERS AND POWER COATING COMPOSITIONS CONTAINING SUCH CROSSLINKERS PPG INDUSTRIES OHIO, INC. (US) 2003-02-13 WO disclosed
WO-2003011970-A1 MODIFIED AMINOPLAST CROSSLINKERS AND POWDER COATING COMPOSITIONS CONTAINING SUCH CROSSLINKERS PPG INDUSTRIES OHIO, INC. (US) 2003-02-13 WO disclosed
US-20020132935-A1 Modified aminoplast crosslinkers and powder coating compositions containing such crosslinkers PPG INDUSTRIES OHIO, INC. 2002-09-19 US disclosed
US-20020071955-A1 Modified aminoplast crosslinkers and powder coating compositions containing such crosslinkers PPG INDUSTRIES OHIO, INC. 2002-06-13 US disclosed
US-20020040112-A1 Modified aminoplast crosslinkers and powder coating compositions containing such crosslinkers PPG INDUSTRIES OHIO, INC. 2002-04-04 US disclosed
US-20020037973-A1 Modified aminoplast crosslinkers and powder coating compositions containing such crosslinkers PPG INDUSTRIES OHIO, INC. 2002-03-28 US disclosed
US-4567139-A ENZYMATIC REACTIONS; MEDICAL DIAGNOSIS BOEHRINGER MANNHEIM GMBH (DE) 1986-01-28 US disclosed
US-4394512-A CHROMOGENS FOR MEASURING HYDROGEN PEROXIDE FORMATION IN ENZYMATI-C REACTION BOEHRINGER MANNHEIM GMBH (DE) 1983-07-19 US disclosed
EP-0033539-B1 USE OF AMINOANTIPYRINE COMPOUNDS AND NEW AMINOANTIPYRINE DERIVATIVES Roche Diagnostics GmbH (DE) 1983-01-19 EP disclosed
EP-0033539-A1 Use of aminoantipyrine compounds and new aminoantipyrine derivatives Roche Diagnostics GmbH (DE) 1981-08-12 EP disclosed