Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL345617 | 1.00 | CA1 (0.46) | CA1TRPA1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2076706 | 0.84 | CA1 (0.43) | CA1SLC1A3SLC1A2SLC1A1TSHR | |
| SCHEMBL31303557 | 0.83 | CA1 (0.47) | CA1TRPA1TSHRCYP2C19KMT2A | |
| SCHEMBL29172647 | 0.83 | CA1 (0.48) | CA1SLC1A3SLC1A2SLC1A1TSHR | |
| SCHEMBL6005452 | 0.81 | TSHR (0.49) | CA1SLC1A3SLC1A2SLC1A1TSHR | |
| SCHEMBL3338742 | 0.81 | CETP (0.44) | CA1SLC1A3SLC1A2SLC1A1TSHR | |
| SCHEMBL2223254 | 0.81 | CA1 (0.47) | CA1TRPA1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1357789 | 0.81 | CA1 (0.47) | CA1TRPA1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2182396 | 0.81 | CA1 (0.47) | CA1TRPA1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL30432293 | 0.81 | L3MBTL1 (0.47) | CA1TSHRMEN1KMT2ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931669-A1 | KINASE INHIBITORS | Takeda San Diego, Inc. (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007044779-A1 | KINASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2007-04-19 | — | — | WO | disclosed |