SCHEMBL4849522

SCHEMBL4849522

c1ccc2c(c1)Cc1c-2ccc2c3c(ccc12)-c1ccccc1C3

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.52
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA4 P22748 1/20 0.47
CA6 P23280 1/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47
HPGD P15428 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
MAOA P21397 1/20 0.44
PGR P06401 1/20 0.42
BCHE P06276 2/20 0.41
CES1 P23141 1/20 0.41
SRD5A2 P31213 1/20 0.41
HTR7 P34969 2/20 0.41
HTR2B P41595 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22263591 0.87 PNMT (0.57) PNMTCA1CA2CA4CA6
SCHEMBL31199126 0.87 HPRT1 (0.50) PNMTCA1CA2CA4CA6
SCHEMBL2486633 0.87 HPRT1 (0.50) PNMTCA1CA2CA4CA6
SCHEMBL28762226 0.84 PNMT (0.44) PNMTCA1CA2CA4CA6
SCHEMBL31406151 0.84 PNMT (0.47) PNMTCA1CA2CA4CA6
SCHEMBL5999581 0.84 PNMT (0.47) PNMTCA1CA2CA4CA6
Benzo(A)Fluorene SCHEMBL150250 0.83 CA1 (0.46) PNMTCA1CA2CA4CA6
Benzo(A)Fluorene SCHEMBL29432662 0.83 CA1 (0.46) PNMTCA1CA2CA4CA6
Benzo(A)Fluorene SCHEMBL29620372 0.83 CA1 (0.46) PNMTCA1CA2CA4CA6
SCHEMBL15674432 0.83 CA1 (0.46) PNMTCA1CA2CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7470290-B2 Hydroscopic polymer gels for easier cleaning THE CLOROX COMPANY (US) 2008-12-30 US disclosed
EP-1966842-A2 LIGHTING ELEMENTS, DEVICES AND METHODS Aldred, Matthew, P. (GB) 2008-09-10 EP disclosed
WO-2007064721-A2 LIGHTING ELEMENTS, DEVICES AND METHODS ALDRED MATTHEW P (GB) 2007-06-07 WO disclosed
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 US disclosed
US-20050245428-A1 Hydroscopic polymer gels for easier cleaning RODRIGUES KLIN A 2005-11-03 US disclosed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US disclosed