SCHEMBL31406151

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4849522	0.84	PNMT (0.52)	PNMTALDH1A1HPGDCYP3A4KDM4E
	SCHEMBL5999581	0.80	PNMT (0.47)	PNMTALDH1A1HPGDCYP3A4KDM4E
	SCHEMBL30497776	0.80	PNMT (0.58)	PNMTALDH1A1HPGDHSD17B10KDM4E
	SCHEMBL221400	0.80	PNMT (0.58)	PNMTALDH1A1HPGDHSD17B10KDM4E
	SCHEMBL31199126	0.79	HPRT1 (0.50)	PNMTALDH1A1HPGDTSHRHSD17B10
	SCHEMBL2486633	0.79	HPRT1 (0.50)	PNMTALDH1A1HPGDTSHRHSD17B10
	SCHEMBL283174	0.79	PNMT (0.53)	PNMTALDH1A1HPGDKDM4ELMNA
	Bromide SCHEMBL28349432	0.78	PNMT (0.56)	PNMTALDH1A1HPGDKDM4ELMNA
	Hydrochloric Acid SCHEMBL2866030	0.78	PNMT (0.56)	PNMTALDH1A1HPGDTSHRKDM4E
	SCHEMBL3630935	0.78	PNMT (0.56)	PNMTALDH1A1HPGDHSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.