Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 10/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20317217 | 0.85 | ADORA2A (0.52) | MAOAKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL22445080 | 0.84 | MAOA (0.68) | MAOAKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL25524554 | 0.82 | MAOA (0.60) | MAOAKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL20346593 | 0.82 | ADORA2A (0.49) | MAOAKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL789119 | 0.81 | MAOA (1.00) | MAOAKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL3649676 | 0.79 | GLA (0.57) | MAOAKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL20317256 | 0.79 | NPC1 (0.53) | MAOAKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL20317249 | 0.79 | NPC1 (0.53) | MAOAKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL27799994 | 0.78 | GLA (0.56) | MAOAKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL20346615 | 0.77 | MAOA (0.55) | MAOAKDM4EALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008048117-A2 | SYNTHESIS OF 5,6-DIMETHYL-9-OXO-9H-XANTHEN-4-YL- ACETIC ACID (DMXAA) | AUCKLAND UNISERVICES LIMITED (NZ) | 2008-04-24 | — | — | WO | disclosed |