SCHEMBL25524554

SCHEMBL25524554

CC#CC(=O)Oc1cccc2c(=O)c3ccccc3oc12

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOA P21397 10/20 0.60
KDM4E B2RXH2 3/20 0.60
ALDH1A1 P00352 2/20 0.60
NPC1 O15118 2/20 0.60
LMNA P02545 1/20 0.60
RAB9A P51151 1/20 0.60
PTGS2 P35354 1/20 0.45
GLA P06280 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
PGAM1 P18669 1/20 0.42
CASP1 P29466 1/20 0.42
CASP7 P55210 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TTR P02766 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4849595 0.82 MAOA (0.68) MAOAKDM4EALDH1A1NPC1LMNA
SCHEMBL789119 0.76 MAOA (1.00) MAOAKDM4EALDH1A1NPC1LMNA
SCHEMBL25524555 0.72 MAPT (0.42) KDM4EALDH1A1NPC1LMNARAB9A
SCHEMBL29006753 0.71 MAOA (0.51) MAOAKDM4EALDH1A1NPC1LMNA
SCHEMBL9576629 0.71 MAOA (0.52) MAOAKDM4EALDH1A1NPC1LMNA
SCHEMBL7113986 0.70 MAOA (0.50) MAOAKDM4EALDH1A1NPC1LMNA
SCHEMBL15485893 0.70 MAOA (0.66) MAOAKDM4EALDH1A1NPC1LMNA
SCHEMBL20317217 0.69 ADORA2A (0.52) MAOAKDM4EALDH1A1NPC1LMNA
SCHEMBL3384509 0.69 KDM4E (0.61) MAOAKDM4EALDH1A1NPC1LMNA
SCHEMBL8711628 0.68 MAOA (0.64) MAOAKDM4EALDH1A1NPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159706-A1 FREE-RADICAL PHOTOINITIATORS AND USES OF SAME IN SILICONE COMPOSITIONS UNIVERSITE DE HAUTE ALSACE (FR) 2023-05-25 US disclosed