Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24322415 | 0.83 | MAPT (0.56) | BCL2EGFRMAPTTSHRALDH1A1 | |
| SCHEMBL2878804 | 0.81 | MAPT (0.43) | MAPTALDH1A1MAPK1HTTGAA | |
| SCHEMBL2028408 | 0.80 | MAPT (0.44) | MAPTALDH1A1MAPK1LMNACYP2C19 | |
| SCHEMBL17459904 | 0.78 | MAPT (0.41) | MAPTALDH1A1MAPK1HTTGAA | |
| SCHEMBL4852978 | 0.77 | LMNA (0.38) | MAPTTSHRACHEALDH1A1MAPK1 | |
| SCHEMBL33651 | 0.75 | MAPT (0.41) | MAPTALDH1A1MAPK1CYP2C19MAOA | |
| SCHEMBL4851308 | 0.75 | MAPT (0.41) | MAPTALDH1A1MAPK1LMNACYP2C19 | |
| SCHEMBL6396649 | 0.75 | CA1 (0.51) | ALDH1A1MAPK1CYP2D6CYP3A4GFER | |
| SCHEMBL5155005 | 0.74 | MAPT (0.43) | MAPTALDH1A1LMNACYP2C19MAOA | |
| SCHEMBL4953767 | 0.73 | MAPT (0.70) | MAPTALDH1A1MAPK1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435268-B2 | N-alkylhydroxylated secondary para-phenylenediamine compounds, composition for dyeing keratin fibers comprising the same, and dyeing processes using the composition | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | claimed |
| US-20060005322-A1 | N-alkylhydroxylated secondary para-phenylenediamine compounds, composition for dyeing keratin fibers comprising the same, and dyeing processes using the composition | L'OREAL S.A. (FR) | 2006-01-12 | — | — | US | claimed |
| EP-1580185-A1 | Secondary n-Alkylhydroxylated p-Phenylendiamins, dye composition for keratin fibers containing them, processes and uses. | L'OREAL (FR) | 2005-09-28 | — | — | EP | claimed |
| US-7435268-B2 | N-alkylhydroxylated secondary para-phenylenediamine compounds, composition for dyeing keratin fibers comprising the same, and dyeing processes using the composition | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |
| US-7435268-B2 | N-alkylhydroxylated secondary para-phenylenediamine compounds, composition for dyeing keratin fibers comprising the same, and dyeing processes using the composition | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |
| US-7435268-B2 | N-alkylhydroxylated secondary para-phenylenediamine compounds, composition for dyeing keratin fibers comprising the same, and dyeing processes using the composition | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |
| US-20060005322-A1 | N-alkylhydroxylated secondary para-phenylenediamine compounds, composition for dyeing keratin fibers comprising the same, and dyeing processes using the composition | L'OREAL S.A. (FR) | 2006-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060005322-A1 | N-alkylhydroxylated secondary para-phenylenediamine compounds, composition for dyeing keratin fibers comprising the same, and dyeing processes using the composition | KRT18, CDC73, PRKDC | BCL2 2878/4885EGFR 1135/4885MAPT 1834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.