Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 5/20 | 0.47 |
| ▸ | ACHE | P22303 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 6/20 | 0.43 |
| ▸ | HRH2 | P25021 | 5/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743300 | 0.85 | HRH3 (0.57) | HRH4BCHEACHEHRH1HRH3 | |
| SCHEMBL4743798 | 0.84 | HRH4 (0.49) | HRH4BCHEACHEKDM4EALDH1A1 | |
| SCHEMBL4746760 | 0.79 | HRH3 (0.51) | HRH4BCHEACHEHRH1HRH3 | |
| SCHEMBL4746684 | 0.78 | HRH4 (0.55) | HRH4BCHEACHEKDM4EALDH1A1 | |
| SCHEMBL4746202 | 0.76 | MAOB (0.54) | — | |
| SCHEMBL4747494 | 0.76 | HRH3 (0.46) | HRH4HRH1HRH2HRH3DRD2 | |
| SCHEMBL4746694 | 0.76 | LSS (0.55) | HRH1HRH2HRH3HTR1ADRD2 | |
| SCHEMBL4746681 | 0.76 | HRH3 (0.46) | HRH4HRH1HRH3DRD2 | |
| SCHEMBL4745404 | 0.75 | F10 (0.49) | HRH4KDM4EALDH1A1HRH1HRH2 | |
| SCHEMBL4743813 | 0.75 | HRH3 (0.55) | HRH4HRH1HRH2HRH3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |