SCHEMBL4851001

SCHEMBL4851001

CCc1ccc(CC)c(C(=O)O)c1CC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.45
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
CA12 O43570 3/20 0.37
PTPN1 P18031 1/20 0.36
PTPN11 Q06124 1/20 0.36
BID P55957 3/20 0.36
MCL1 Q07820 3/20 0.36
BCL2L1 Q07817 2/20 0.36
BAK1 Q16611 2/20 0.36
KAT8 Q9H7Z6 2/20 0.36
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
EP300 Q09472 1/20 0.36
KAT2A Q92830 1/20 0.36
KAT2B Q92831 1/20 0.36
KAT5 Q92993 1/20 0.36
SAE1 Q9UBE0 1/20 0.36
METAP2 P50579 2/20 0.36
ADORA3 P0DMS8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL75798 0.85 ALDH1A1 (0.41) ALDH1A1RXRARXRBBIDMCL1
SCHEMBL28552687 0.85 ALDH1A1 (0.41) ALDH1A1RXRARXRBBIDMCL1
SCHEMBL207494 0.85 GABRP (0.41) ALDH1A1RXRARXRBCA12BID
SCHEMBL17911667 0.84 GABRP (0.40) ALDH1A1RXRARXRBBIDMCL1
SCHEMBL28943131 0.84 GABRP (0.40) ALDH1A1RXRARXRBCA12METAP2
Acetic Acid SCHEMBL10946506 0.82 GABRP (0.39) ALDH1A1RXRARXRBCA12METAP2
Cyclohexane SCHEMBL7802327 0.81 GABRP (0.38) ALDH1A1RXRARXRBMETAP2GABRA1
Phthalic Acid SCHEMBL10963447 0.79 ALDH1A1 (0.48) ALDH1A1
Phthalic Acid SCHEMBL29429444 0.79 ALDH1A1 (0.48) ALDH1A1
SCHEMBL8879901 0.78 GABRP (0.42) ALDH1A1RXRARXRBCA12PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0187462-B1 SUPPORTED OLEFIN POLYMERIZATION CATALYST AMOCO CORPORATION (US) 1990-04-25 EP claimed
US-7371866-B2 Preparation of aromatic and heteroaromatic carboxylic acids by catalytic ozonolysis DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2008-05-13 US disclosed
WO-2005063385-A1 METHOD FOR OXIDIZING SATURATED HYDROCARBONS DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2005-07-14 WO disclosed
US-20030216577-A1 Preparation of aromatic and heteroaromatic carboxylic acids by catalytic ozonolysis DSM FINE CHEMICALS AUSTRIA NFG GMBH & COKG (AT) 2003-11-20 US disclosed
EP-1362840-A1 Process for the preparation of aromatic and heteroaromatic carboxylic acids via catalytic ozonolysis DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) 2003-11-19 EP disclosed