Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.34 |
| ▸ | WEE1 | P30291 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 2/20 | 0.31 |
| ▸ | INSR | P06213 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 2/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.30 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4851697 | 1.00 | MAPK14 (0.35) | MAPK14FGFR1WEE1LMNAEGFR | |
| SCHEMBL14158987 | 0.90 | CSF1R (0.33) | MAPK14FGFR1WEE1KDM4EADORA2A | |
| SCHEMBL14163890 | 0.90 | CSF1R (0.33) | MAPK14FGFR1WEE1KDM4EADORA2A | |
| SCHEMBL4848856 | 0.85 | MAPK14 (0.41) | MAPK14FGFR1WEE1 | |
| SCHEMBL4848848 | 0.85 | MAPK14 (0.41) | MAPK14FGFR1WEE1 | |
| SCHEMBL4855851 | 0.82 | MAPT (0.41) | LMNAKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4855855 | 0.82 | MAPT (0.41) | LMNAKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4854511 | 0.81 | MAPT (0.38) | FGFR1LMNAKDM4ENPC1RAB9A | |
| SCHEMBL4854506 | 0.81 | MAPT (0.38) | FGFR1LMNAKDM4ENPC1RAB9A | |
| SCHEMBL4856513 | 0.80 | MAPK14 (0.36) | MAPK14FGFR1WEE1EGFRADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139588-A1 | Pyrrolo[2,3-d]pyrimidine cytokine inhibitors | THE PROCTER & GAMBLE COMPANY | 2008-06-12 | — | — | US | disclosed |
| US-7319102-B1 | Pyrrolo[2,3-d]pyrimidine cytokine inhibitors | THE PROCTER & GAMBLE COMPANY (US) | 2008-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139588-A1 | Pyrrolo[2,3-d]pyrimidine cytokine inhibitors | DPYD, IL1B, IL6 | MAPK14 2806/4885FGFR1 573/4885WEE1 2835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.