SCHEMBL4851840

SCHEMBL4851840

C1=Cc2c3cc4cc5ccccc5cc4cc3cc3cccc1c23

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.36
ERBB2 P04626 1/20 0.36
FYN P06241 1/20 0.36
MAOA P21397 1/20 0.36
ACHE P22303 1/20 0.36
AHR P35869 1/20 0.36
ALDH1A1 P00352 7/20 0.33
GAA P10253 3/20 0.33
KDM4E B2RXH2 2/20 0.33
HSD17B10 Q99714 4/20 0.32
HIF1A Q16665 3/20 0.32
CASP1 P29466 2/20 0.32
CASP7 P55210 2/20 0.32
HPGD P15428 2/20 0.32
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
CYP3A4 P08684 1/20 0.32
ALOX15 P16050 1/20 0.32
HBB P68871 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4848697 0.98 CYP1A2 (0.37) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4850326 0.86 ALDH1A1 (0.52) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL29562021 0.85 CYP1A2 (0.47) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL26028 0.85 CYP1A2 (0.47) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4853798 0.84 CYP1A2 (0.44) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4853248 0.84 CYP1A2 (0.43) CYP1A2ERBB2FYNMAOAACHE
Triphenylene SCHEMBL22493025 0.83 CYP1A2 (0.46) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4852228 0.83 ALDH1A1 (0.49) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4845200 0.79 ALDH1A1 (0.45) CYP1A2ERBB2FYNMAOAACHE
Benzo[J]Aceanthrylene SCHEMBL1289323 0.79 CYP1A2 (0.46) CYP1A2ERBB2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7470290-B2 Hydroscopic polymer gels for easier cleaning THE CLOROX COMPANY (US) 2008-12-30 US disclosed
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 US disclosed
US-20050245428-A1 Hydroscopic polymer gels for easier cleaning RODRIGUES KLIN A 2005-11-03 US disclosed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US disclosed