Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2608232 | 0.90 | ZDHHC20 (0.47) | MEN1KMT2AZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL20798489 | 0.86 | MEN1 (0.44) | MEN1KMT2AZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL12328966 | 0.86 | TSHR (0.52) | MEN1KMT2AZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL12213321 | 0.86 | TSHR (0.52) | MEN1KMT2AZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL4361183 | 0.86 | TSHR (0.52) | MEN1KMT2AZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL12328384 | 0.86 | TSHR (0.52) | MEN1KMT2AZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL10064051 | 0.84 | TSHR (0.54) | MEN1KMT2AZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL18721198 | 0.83 | MEN1 (0.47) | MEN1KMT2AZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL20459821 | 0.83 | KMT2A (0.56) | MEN1KMT2AZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL3109503 | 0.83 | ALDH1A1 (0.56) | KMT2AZDHHC20ZDHHC2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7329694-B2 | Ocular lens | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2008-02-12 | — | — | US | claimed |
| US-7329694-B2 | Ocular lens | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2008-02-12 | — | — | US | disclosed |
| US-20040201820-A1 | Ocular lens | JOHNSON & JOHNSON VISION CARE, INC. | 2004-10-14 | — | — | US | disclosed |
| EP-1445641-A1 | OCULAR LENS | Johnson & Johnson Vision Care, Inc. (US) | 2004-08-11 | — | — | EP | disclosed |