Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP10 | P09238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2341926 | 0.70 | SMN1; SMN2 (0.48) | KMT2ASMN1; SMN2 | |
| SCHEMBL28050943 | 0.66 | TLR9 (0.34) | KMT2ASMN1; SMN2 | |
| SCHEMBL10096968 | 0.65 | SMN1; SMN2 (0.38) | KMT2ASMN1; SMN2 | |
| SCHEMBL4852373 | 0.65 | OPRM1 (0.46) | HTR6KMT2ASMN1; SMN2 | |
| SCHEMBL7751891 | 0.64 | OPRM1 (0.41) | HTR6KMT2ASMN1; SMN2MMP3MMP10 | |
| SCHEMBL27944713 | 0.64 | DHODH (0.34) | KMT2ASMN1; SMN2 | |
| SCHEMBL11332992 | 0.63 | SMN1; SMN2 (0.49) | KMT2ASMN1; SMN2 | |
| Methyl Alcohol SCHEMBL11717390 | 0.63 | KMT2A (0.41) | HTR6KMT2ASMN1; SMN2 | |
| SCHEMBL10611492 | 0.62 | SMN1; SMN2 (0.51) | KMT2ASMN1; SMN2 | |
| SCHEMBL7056971 | 0.60 | SMN1; SMN2 (0.53) | KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008126106-A2 | NOVEL AND IMPROVED PROCESSES FOR THE PREPARATION OF INTERMEDIATES OF DARIFENACIN, DARIFENACIN AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS | SATYANARAYANA REDDY MANNE (IN) | 2008-10-23 | — | — | WO | disclosed |