Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7751891 | 0.79 | OPRM1 (0.41) | OPRM1HTR6VDRKMT2AMEN1 | |
| SCHEMBL5553083 | 0.72 | HTR6 (0.41) | HTR6VDRKMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3251133 | 0.68 | OPRM1 (0.51) | OPRM1 | |
| SCHEMBL2341926 | 0.66 | SMN1; SMN2 (0.48) | VDRKMT2AALDH1A1SMN1; SMN2CYP2C19 | |
| SCHEMBL10267011 | 0.66 | OPRM1 (0.47) | OPRM1APP | |
| SCHEMBL4852379 | 0.65 | HTR6 (0.32) | HTR6KMT2ASMN1; SMN2 | |
| SCHEMBL20300353 | 0.65 | HTR6 (0.40) | OPRM1HTR6VDRKMT2AMEN1 | |
| SCHEMBL27546626 | 0.64 | OPRM1 (0.44) | OPRM1APP | |
| SCHEMBL7056971 | 0.63 | SMN1; SMN2 (0.53) | VDRKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11332992 | 0.63 | SMN1; SMN2 (0.49) | VDRKMT2AALDH1A1SMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008126106-A2 | NOVEL AND IMPROVED PROCESSES FOR THE PREPARATION OF INTERMEDIATES OF DARIFENACIN, DARIFENACIN AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS | SATYANARAYANA REDDY MANNE (IN) | 2008-10-23 | — | — | WO | disclosed |