SCHEMBL4853349

SCHEMBL4853349

N#CC1=C(Cl)C(=O)C(Cl)=CC1=O

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
AURKA O14965 1/20 0.32
AURKB Q96GD4 1/20 0.32
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
ALOX12 P18054 1/20 0.30
RECQL P46063 1/20 0.30
KMT2A Q03164 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylene Chloride SCHEMBL28857353 0.94
Tetrahydrofuran SCHEMBL28255395 0.86 MAPK1 (0.30)
SCHEMBL10444864 0.84 AURKA (0.32) AURKAAURKBMEN1ALDH1A1MAPT
SCHEMBL28116401 0.81
SCHEMBL1387747 0.73 CES2 (0.44) MEN1ALDH1A1MAPTHPGDALOX12
SCHEMBL27669033 0.71
SCHEMBL1890738 0.71 MAPT (0.44) AURKAAURKBMEN1ALDH1A1MAPT
SCHEMBL244289 0.71 CES2 (0.44) MEN1ALDH1A1MAPTHPGDALOX12
SCHEMBL3688719 0.68
SCHEMBL2952 0.68 MEN1 (0.47) MEN1ALDH1A1MAPTHPGDALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119490551-A Preparation method of dydrogesterone 湖北葛店人福药业有限责任公司 2025-02-21 CN claimed
EP-3098284-B1 NEAR-ULTRAVIOLET STIMULATED LIGHT-EMITTING COMPOUND AND PRODUCTION METHOD FOR SAME NANO CMS CO LTD (KR) 2024-09-04 EP claimed
CN-110483435-A A kind of fluorine-containing benzoxazoles liquid-crystal compounds and its synthetic method of big birefringence UNIV SHAANXI NORMAL 2019-11-22 CN claimed
CN-110483434-A Big birefringence side fluorine benzoxazoles liquid-crystal compounds containing acetylene bond and preparation method thereof UNIV SHAANXI NORMAL 2019-11-22 CN claimed
CN-110483292-A A kind of preparation method of repaglinide key intermediate Hangzhou zhongmei huadong pharmaceutical co ltd 2019-11-22 CN claimed
CN-107082771-B Double alpha-cyano imines substituted isochroman class compounds and its synthetic method 上海大学 2019-11-19 CN claimed
CN-110437846-A Fluorine containing acetylene bond replaces benzoxazoles liquid-crystal compounds and preparation method thereof UNIV SHAANXI NORMAL 2019-11-12 CN claimed
CN-108017682-B A kind of synthetic method of trenbolone acetate 浙江仙居君业药业有限公司 2019-11-08 CN claimed
CN-110240554-A α-thioether aryl acetonitrile compound and its synthetic method 上海大学 2019-09-17 CN claimed
CN-107367495-B A kind of sedimentation type alkaline phosphatase fluorescence probe and its synthetic method and application 湖南大学 2019-09-06 CN claimed
CN-108047299-A The preparation method of canrenone important intermediate 广西万德药业有限公司 2018-05-18 CN claimed
CN-108017682-A A kind of synthetic method of trenbolone acetate 浙江仙居君业药业有限公司 2018-05-11 CN claimed
CN-106432315-B A kind of preparation method and application of the Cys fluorescence probes based on fluorine boron pyrroles 湘潭大学 2018-05-08 CN claimed
CN-106083803-B A kind of synthetic method of marine natural products Puupehedione 威海惠安康生物科技有限公司 2018-05-04 CN claimed
US-20170012218-A1 NEAR-ULTRAVIOLET STIMULATED LIGHT-EMITTING COMPOUND AND PRODUCTION METHOD FOR SAME NANO CMS CO., LTD. (KR) 2017-01-12 US claimed
EP-3098284-A1 NEAR-ULTRAVIOLET STIMULATED LIGHT-EMITTING COMPOUND AND PRODUCTION METHOD FOR SAME Nano CMS Co., Ltd. (KR) 2016-11-30 EP claimed
EP-0606453-B1 PHOTOVOLTAIC CELL ASULAB SA (CH) 1997-06-04 EP claimed
US-5482570-A Photovoltaic cell ASULAB S.A. (CH) 1996-01-09 US claimed
EP-0606453-A1 PHOTOVOLTAIC CELL. ASULAB SA (CH) 1994-07-20 EP claimed
WO-1994003930-A1 PHOTOVOLTAIC CELL ASULAB S.A. (CH) 1994-02-17 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170012218-A1 NEAR-ULTRAVIOLET STIMULATED LIGHT-EMITTING COMPOUND AND PRODUCTION METHOD FOR SAME SUN2, TYR, SQLE AURKA 1566/4885AURKB 2317/4885MEN1 1021/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.