Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12500062 | 0.85 | MEN1 (0.39) | CES2BCHEACHECES1MEN1 | |
| SCHEMBL1387747 | 0.85 | CES2 (0.44) | CES2BCHEACHECES1MEN1 | |
| SCHEMBL12954420 | 0.79 | KDM4E (0.30) | CES2BCHEACHECES1MEN1 | |
| SCHEMBL375015 | 0.79 | MEN1 (0.47) | CES2BCHEACHECES1MEN1 | |
| Water SCHEMBL28189365 | 0.79 | MEN1 (0.47) | CES2BCHEACHECES1MEN1 | |
| SCHEMBL2952 | 0.79 | MEN1 (0.47) | CES2BCHEACHECES1MEN1 | |
| SCHEMBL615573 | 0.77 | MEN1 (0.31) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL28071586 | 0.77 | CES2 (0.44) | CES2BCHEACHECES1MEN1 | |
| Hydrochloric Acid SCHEMBL8130707 | 0.77 | CES2 (0.44) | CES2BCHEACHECES1MEN1 | |
| SCHEMBL9196667 | 0.74 | CES2 (0.42) | CES2BCHEACHECES1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805398-A | Preparation method of ecteinascidin compound | 江苏恒瑞医药股份有限公司 | 2022-07-29 | — | — | CN | claimed |
| US-20230227393-A1 | IRON CATALYZED HIGHLY ENANTIOSELECTIVE CIS-DIHYDROXYLATION OF QUINONES | THE UNIVERSITY OF HONG KONG (CN) | 2023-07-20 | — | — | US | disclosed |
| US-11584717-B2 | MIF modulators | YALE UNIVERSITY (US) | 2023-02-21 | — | — | US | disclosed |
| CN-113135855-B | Preparation method of papaverine compound | 江苏恒瑞医药股份有限公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-114805398-A | Preparation method of ecteinascidin compound | 江苏恒瑞医药股份有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-113135855-A | Preparation method of papaverine compound | 江苏恒瑞医药股份有限公司 | 2021-07-20 | — | — | CN | disclosed |
| WO-2021057998-A1 | PREPARATION METHOD FOR PYRROLOAMINOPYRIDAZINONE COMPOUND | 上海森辉医药有限公司 | 2021-04-01 | — | — | WO | disclosed |
| US-20200377457-A1 | MIF MODULATORS | UNIV YALE (US) | 2020-12-03 | — | — | US | disclosed |
| US-20190270706-A1 | MIF MODULATORS | UNIV YALE (US) | 2019-09-05 | — | — | US | disclosed |
| US-10202343-B2 | MIF modulators | YALE UNIVERSITY (US) | 2019-02-12 | — | — | US | disclosed |
| EP-1737841-A1 | PYRAZINE DERIVATIVES AND PHARMACEUTICAL USE THEREOF AS ADENOSINE ANTAGONISTS | Astellas Pharma Inc. (JP) | 2007-01-03 | — | — | EP | disclosed |
| US-20060083890-A1 | Two-photon absorption decolorizable material, two-photon absorption refractive index modulation material, two-photon absorption polymerization material, two-photon absorption polymerization method and three-dimensional optical recording material | FUJI PHOTO FILM CO., LTD. (JP) | 2006-04-20 | — | — | US | disclosed |
| US-20060057467-A1 | Hologram recording material and hologram recording method | FUJI PHOTO FILM CO., LTD. | 2006-03-16 | — | — | US | disclosed |
| WO-2005095384-A1 | PYRAZINE DERIVATIVES AND PHARMACEUTICAL USE THEREOF AS ADENOSINE ANTAGONISTS | ASTELLAS PHARMA INC. (JP) | 2005-10-13 | — | — | WO | disclosed |
| US-20050058910-A1 | Hologram recording method and hologram recording material | FUJI PHOTO FILM CO., LTD. | 2005-03-17 | — | — | US | disclosed |
| US-20050046915-A1 | Hologram recording material composition, hologram recording material and hologram recording method | FUJI PHOTO FILM CO., LTD. | 2005-03-03 | — | — | US | disclosed |
| EP-1510862-A2 | Hologram recording method and hologram recording material | Fuji Photo Film Co., Ltd. (JP) | 2005-03-02 | — | — | EP | disclosed |
| EP-1508833-A2 | Hologram recording material composition, hologram recording material and hologram recording method | FUJI PHOTO FILM CO., LTD. (JP) | 2005-02-23 | — | — | EP | disclosed |
| US-20050003133-A1 | Two-photon absorbing optical recording material and two-photon absorbing optical recording and reproducing method | FUJI PHOTO FILM CO., LTD. | 2005-01-06 | — | — | US | disclosed |
| US-20040245432-A1 | Two-photon absorbing polymerization method, two-photon absorbing optical recording material and two-photon absorbing optical recording method | FUJI PHOTO FILM CO., LTD. | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11584717-B2 | MIF modulators | MIF, HMGB2, HMGB3 | CES2 3336/4885BCHE 4641/4885ACHE 4704/4885 |
| US-20230227393-A1 | IRON CATALYZED HIGHLY ENANTIOSELECTIVE CIS-DIHYDROXYLATION OF QUINONES | NFE2L2, DUOX1, DUOX2 | CES2 2599/4885BCHE 1262/4885ACHE 1283/4885 |
| US-20200377457-A1 | MIF MODULATORS | MIF, HMGB2, HMGB3 | CES2 3336/4885BCHE 4641/4885ACHE 4704/4885 |
| US-10202343-B2 | MIF modulators | MIF, HMGB2, HMGB3 | CES2 3336/4885BCHE 4641/4885ACHE 4704/4885 |
| US-20190270706-A1 | MIF MODULATORS | MIF, HMGB2, HMGB3 | CES2 3336/4885BCHE 4641/4885ACHE 4704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.