Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.77 |
| ▸ | NPC1 | O15118 | 7/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3843864 | 0.71 | NPC1 (0.43) | RAB9ANPC1SMN1; SMN2ALDH1A1HSD11B1 | |
| Bromide SCHEMBL3849521 | 0.69 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL9781931 | 0.69 | F2 (0.62) | RAB9ANPC1SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL6224695 | 0.68 | RAB9A (1.00) | RAB9ANPC1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL6199337 | 0.68 | RAB9A (1.00) | RAB9ANPC1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL1753283 | 0.68 | RAB9A (0.85) | RAB9ANPC1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL16080089 | 0.68 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL22286589 | 0.67 | SMN1; SMN2 (0.53) | RAB9ANPC1SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL8303468 | 0.66 | NPC1 (0.55) | RAB9ANPC1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL7850769 | 0.66 | RAB9A (0.55) | RAB9ANPC1ALDH1A1HSD11B1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7345009-B2 | Reacting 4-phenyl pyraoline compound with phenyl isocyanate compound | BAYER CROPSCIENCE AG (DE) | 2008-03-18 | — | — | US | disclosed |
| US-20080064732-A1 | Substituted 4-hetarylpyrazolines | MAURER FRITZ | 2008-03-13 | — | — | US | disclosed |
| US-20050119128-A1 | Substituted 4-hetaryl-pyrazolines as pest control agents | BAYER CROPSCIENCE AG (DE) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064732-A1 | Substituted 4-hetarylpyrazolines | CYP4F3, CYP4X1, CYP4B1 | RAB9A 363/4885NPC1 2611/4885SMN1; SMN2 2890/4885 |
| US-20050119128-A1 | Substituted 4-hetaryl-pyrazolines as pest control agents | CYP4X1, CYP4F3, DDT | RAB9A 235/4885NPC1 3726/4885SMN1; SMN2 4010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.