SCHEMBL4854329

SCHEMBL4854329

O=C(O)CCCCC(F)F

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.58
NFKB1 P19838 2/20 0.55
TSHR P16473 2/20 0.55
PMP22 Q01453 1/20 0.55
GSTK1 Q9Y2Q3 2/20 0.52
SLC22A6 Q4U2R8 2/20 0.50
ENPEP Q07075 1/20 0.50
FFAR4 Q5NUL3 2/20 0.48
FFAR1 O14842 2/20 0.48
ALDH1A1 P00352 2/20 0.47
GPR84 Q9NQS5 2/20 0.46
AKR1B1 P15121 1/20 0.46
CYP2D6 P10635 1/20 0.46
FOLH1 Q04609 1/20 0.46
SLC22A8 Q8TCC7 1/20 0.44
PPARG P37231 1/20 0.44
PPARD Q03181 1/20 0.44
PPARA Q07869 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21895805 0.97 TSHR (0.60) LMNANFKB1TSHRPMP22GSTK1
SCHEMBL1032258 0.92
Hydrochloric Acid SCHEMBL26919967 0.90 LMNA (0.50) LMNANFKB1TSHRPMP22GSTK1
SCHEMBL27804244 0.82 LMNA (0.55) LMNANFKB1TSHRPMP22GSTK1
SCHEMBL1032360 0.80
SCHEMBL7782357 0.80 LMNA (0.52) LMNANFKB1TSHRPMP22GSTK1
SCHEMBL22826568 0.80 MAPT (0.59) LMNANFKB1TSHRPMP22GSTK1
SCHEMBL21895793 0.78 TSHR (0.55) LMNANFKB1TSHRPMP22GSTK1
Hydrochloric Acid SCHEMBL7410571 0.78
Adipic Acid SCHEMBL2244299 0.76 LMNA (1.00) LMNANFKB1TSHRPMP22SLC22A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112042016-B Lithium cobalt oxide secondary battery for high voltage applications comprising a fluorinated electrolyte and a positive electrode material 尤米科尔公司 2023-10-20 CN claimed
CN-114762147-A Electrolyte compositions with fluorinated acyclic esters and fluorinated cyclic carbonates 索尔维公司 2022-07-15 CN claimed
CN-112186247-A Non-aqueous electrolyte of lithium ion battery, lithium ion battery and manufacturing method 重庆市紫建电子股份有限公司 2021-01-05 CN claimed
CN-112042016-A Lithium cobalt oxide secondary battery comprising fluorinated electrolyte and positive electrode material for high voltage applications 尤米科尔公司 2020-12-04 CN claimed
CN-111512488-A Non-aqueous electrolyte composition comprising lithium bis (fluorosulfonyl) imide 索尔维公司 2020-08-07 CN claimed
CN-112687952-B Electrolyte, electrochemical device, and electronic device 宁德新能源科技有限公司 2023-12-08 CN disclosed
CN-112042016-B Lithium cobalt oxide secondary battery for high voltage applications comprising a fluorinated electrolyte and a positive electrode material 尤米科尔公司 2023-10-20 CN disclosed
WO-2023081612-A1 METHODS OF TREATING PATIENTS HAVING TYPE 1 DIABETES WITH EFLORNITHINE CANCER PREVENTION PHARMACEUTICALS, INC. (US) 2023-05-11 WO disclosed
US-11534434-B2 Xanomeline derivatives and methods for treating neurological disorders Karuna Therapeutics, Inc. (US) 2022-12-27 US disclosed
CN-114762170-A Electrolyte compositions with fluorinated acyclic carbonates and fluorinated cyclic carbonates 索尔维公司 2022-07-15 CN disclosed
EP-3968971-A1 METHODS FOR TREATING FAMILIAL ADENOMATOUS POLYPOSIS Cancer Prevention Pharmaceuticals, Inc. (US) 2022-03-23 EP disclosed
CN-114142085-A Non-aqueous electrolyte of lithium ion battery, lithium ion battery and preparation method of lithium ion battery 重庆市紫建新能源有限公司 2022-03-04 CN disclosed
CN-112186247-A Non-aqueous electrolyte of lithium ion battery, lithium ion battery and manufacturing method 重庆市紫建电子股份有限公司 2021-01-05 CN disclosed
CN-112042015-A Ni-based lithium ion secondary battery comprising fluorinated electrolyte 尤米科尔公司 2020-12-04 CN disclosed
CN-112042016-A Lithium cobalt oxide secondary battery comprising fluorinated electrolyte and positive electrode material for high voltage applications 尤米科尔公司 2020-12-04 CN disclosed
WO-2020236562-A1 METHODS FOR TREATING FAMILIAL ADENOMATOUS POLYPOSIS CANCER PREVENTION PHARMACEUTICALS, INC. (US) 2020-11-26 WO disclosed
EP-3368029-A1 EFLORNITHINE AND SULINDAC, FIXED DOSE COMBINATION FORMULATION Cancer Prevention Pharmaceuticals, Inc. (US) 2018-09-05 EP disclosed
WO-2017075576-A1 EFLORNITHINE AND SULINDAC, FIXED DOSE COMBINATION FORMULATION CANCER PREVENTION PHARMACEUTICALS, INC. (US) 2017-05-04 WO disclosed
US-7345192-B2 Reduction of hair growth THE GILLETTE COMPANY (US) 2008-03-18 US disclosed
US-20060067903-A1 Using 2-difluoromethylornithine THE GILLETTE COMPANY, A DELAWARE CORPORATION 2006-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060067903-A1 Using 2-difluoromethylornithine FGF2, FGF1, KRT18 LMNA 4617/4885NFKB1 3293/4885TSHR 2423/4885
US-11534434-B2 Xanomeline derivatives and methods for treating neurological disorders CHRM1, RXFP3, NPY5R LMNA 1087/4885NFKB1 3175/4885TSHR 164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.