Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4860148 | 0.93 | RECQL (0.81) | RECQLTSHRKDM4EHPGDCYP1A2 | |
| SCHEMBL8366672 | 0.88 | RECQL (0.79) | RECQLTSHRKDM4EHPGDCYP1A2 | |
| SCHEMBL10599988 | 0.87 | RECQL (0.77) | RECQLTSHRKDM4EHPGDCYP1A2 | |
| SCHEMBL14112030 | 0.87 | RECQL (0.77) | RECQLTSHRKDM4EHPGDCYP1A2 | |
| SCHEMBL10475269 | 0.84 | RECQL (0.71) | RECQLTSHRKDM4EHPGDCYP1A2 | |
| SCHEMBL8184182 | 0.83 | RECQL (0.70) | RECQLTSHRKDM4EHPGDCYP1A2 | |
| SCHEMBL11253171 | 0.81 | NPC1 (0.60) | RECQLTSHRKDM4EHPGDCYP1A2 | |
| SCHEMBL6539069 | 0.80 | TSHR (0.67) | RECQLTSHRSIRT3ALDH1A1 | |
| Ethylamine SCHEMBL27389141 | 0.78 | ALOX15 (0.59) | KDM4EHPGDNPC1KMT2ASMN1; SMN2 | |
| SCHEMBL28724172 | 0.78 | TSHR (0.68) | RECQLTSHRKDM4EHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7355074-B2 | Compounds having aromatic rings and side-chain amide-functionality and a method for transporting monovalent anions across biological membranes using the same | THE UNIVERSITY OF MARYLAND (US) | 2008-04-08 | — | — | US | disclosed |