Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.81 |
| ▸ | TSHR | P16473 | 1/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALPL | P05186 | 1/20 | 0.57 |
| ▸ | ALPI | P09923 | 1/20 | 0.57 |
| ▸ | ALPG | P10696 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8366672 | 0.95 | RECQL (0.79) | RECQLTSHRKDM4EHPGDCYP1A2 | |
| SCHEMBL14112030 | 0.94 | RECQL (0.77) | RECQLTSHRKDM4EHPGDCYP1A2 | |
| SCHEMBL10599988 | 0.94 | RECQL (0.77) | RECQLTSHRKDM4EHPGDCYP1A2 | |
| SCHEMBL4854595 | 0.93 | RECQL (0.71) | RECQLTSHRKDM4EHPGDCYP1A2 | |
| SCHEMBL10475269 | 0.90 | RECQL (0.71) | RECQLTSHRKDM4EHPGDCYP1A2 | |
| SCHEMBL8184182 | 0.90 | RECQL (0.70) | RECQLTSHRKDM4EHPGDCYP1A2 | |
| SCHEMBL6539069 | 0.86 | TSHR (0.67) | RECQLTSHRALDH1A1SIRT3 | |
| SCHEMBL28724172 | 0.84 | TSHR (0.68) | RECQLTSHRKDM4EHPGDNPC1 | |
| SCHEMBL7373683 | 0.84 | RECQL (0.63) | RECQLTSHRKDM4EHPGDCYP1A2 | |
| SCHEMBL4737165 | 0.84 | HTT (0.78) | RECQLTSHRHPGDKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7355074-B2 | Compounds having aromatic rings and side-chain amide-functionality and a method for transporting monovalent anions across biological membranes using the same | THE UNIVERSITY OF MARYLAND (US) | 2008-04-08 | — | — | US | disclosed |
| US-20050009921-A1 | Compounds having aromatic rings and side-chain amide-functionality and a method for transporting monovalent anions across biological membranes using the same | MARYLAND, UNIVERSITY OF | 2005-01-13 | — | — | US | disclosed |
| US-6277871-B1 | ANTICANCER AGENTS | ABBOTT LABORATORIES | 2001-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009921-A1 | Compounds having aromatic rings and side-chain amide-functionality and a method for transporting monovalent anions across biological membranes using the same | SLC26A3, SLC22A8, SLC43A1 | RECQL 2332/4885TSHR 2124/4885KDM4E 3115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.