⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30055270 | 0.98 | ALDH1A1 (0.44) | — | |
| Pyrrole SCHEMBL28968028 | 0.89 | ALDH1A1 (0.38) | — | |
| SCHEMBL29261126 | 0.84 | ALDH1A1 (0.35) | — | |
| SCHEMBL496650 | 0.68 | — | — | |
| SCHEMBL5170029 | 0.67 | ALDH1A1 (0.59) | — | |
| Purine SCHEMBL29703771 | 0.65 | ALDH1A1 (0.47) | — | |
| Purine SCHEMBL2120554 | 0.65 | ALDH1A1 (0.47) | — | |
| Purine SCHEMBL29365913 | 0.65 | — | — | |
| Purine SCHEMBL3158 | 0.65 | — | — | |
| SCHEMBL30110227 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 357 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516637-B1 | THERMOSTABLE BIOCATALYST COMBINATION FOR NUCLEOSIDE SYNTHESIS | PLASMIA BIOTECH S L (ES) | 2016-04-20 | — | — | EP | claimed |
| CN-102770532-A | Thermostable biocatalyst conjugates for nucleoside synthesis | PLASMIA BIOTECH S L | 2012-11-07 | — | — | CN | claimed |
| EP-2516637-A1 | THERMOSTABLE BIOCATALYST COMBINATION FOR NUCLEOSIDE SYNTHESIS | Plasmia Biotech, S.L. (ES) | 2012-10-31 | — | — | EP | claimed |
| US-20120264175-A1 | THERMOSTABLE BIOCATALYST COMBINATION FOR NUCLEOSIDE SYNTHESIS | BRILL ENGINES, S.L. (ES) | 2012-10-18 | — | — | US | claimed |
| WO-2011076894-A1 | THERMOSTABLE BIOCATALYST COMBINATION FOR NUCLEOSIDE SYNTHESIS | INSTITUT UNIV. DE CIÈNCIA I TECNOLOGIA, S.A. (ES) | 2011-06-30 | — | — | WO | claimed |
| EP-2338985-A1 | Thermostable biocatalyst combination for nucleoside synthesis | Institut Univ. de Ciència i Tecnologia, s.a. (ES) | 2011-06-29 | — | — | EP | claimed |
| US-7781189-B2 | Catalyzing transglycosylation using a recombinant host cell overexpressing uridine phosphorylase and purine nucleoside phosphorylase | BIO-KER S.R.L. (IT) | 2010-08-24 | — | — | US | claimed |
| EP-1214331-B1 | 2-AZAPURINE COMPOUNDS AND THEIR USE | ROCHE DIAGNOSTICS GMBH (DE) | 2006-10-11 | — | — | EP | claimed |
| US-20050142645-A1 | Vectors, host cells, and methods for production of uridine phosphorylase and purine nucleotide phosphorylase | KERYOS SPA (IT) | 2005-06-30 | — | — | US | claimed |
| EP-1141328-B1 | RECOMBINANT BACTERIAL STRAINS FOR THE PRODUCTION OF NATURAL NUCLEOSIDES AND MODIFIED ANALOGUES THEREOF | KERYOS SPA (IT) | 2004-09-29 | — | — | EP | claimed |
| US-5478928-A | Useful as antiviral agents in the treatment and prevention of AIDS | SOUTHERN RESEARCH INSTITUTE (US) | 1995-12-26 | — | — | US | claimed |
| WO-1995011685-A1 | 2',3'-DIDEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AGENTS | SOUTHERN RESEARCH INSTITUTE (US) | 1995-05-04 | — | — | WO | claimed |
| WO-1994001117-A1 | THERAPEUTIC NUCLEOSIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-01-20 | — | — | WO | claimed |
| EP-0525106-A4 | 2',3'-DIDEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AGENTS | — | 1993-04-21 | — | — | EP | claimed |
| EP-0491793-A4 | 2'-DEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AND ANTICANCER AGENTS | — | 1993-03-03 | — | — | EP | claimed |
| EP-0525106-A1 | 2',3'-DIDEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AGENTS | SOUTHERN RESEARCH INSTITUTE (US) | 1993-02-03 | — | — | EP | claimed |
| US-5128458-A | 2',3'-dideoxy-4'-thioribonucleosides as antiviral agents | SOUTHERN RESEARCH INSTITUTE (US) | 1992-07-07 | — | — | US | claimed |
| EP-0491793-A1 | 2'-DEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AND ANTICANCER AGENTS | SOUTHERN RESEARCH INSTITUTE (US) | 1992-07-01 | — | — | EP | claimed |
| WO-1991016333-A1 | 2',3'-DIDEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AGENTS | SOUTHERN RESEARCH INSTITUTE (US) | 1991-10-31 | — | — | WO | claimed |
| WO-1991004033-A1 | 2'-DEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AND ANTICANCER AGENTS | SOUTHERN RESEARCH INSTITUTE (US) | 1991-04-04 | — | — | WO | claimed |