⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Purine SCHEMBL6421380 | 1.00 | ALDH1A1 (0.47) | — | |
| Purine SCHEMBL29703771 | 1.00 | ALDH1A1 (0.47) | — | |
| Purine SCHEMBL2120554 | 1.00 | ALDH1A1 (0.47) | — | |
| Purine SCHEMBL30862524 | 1.00 | — | — | |
| Purine SCHEMBL3158 | 1.00 | — | — | |
| Purine SCHEMBL6438164 | 0.98 | ALDH1A1 (0.45) | — | |
| Purine SCHEMBL31212689 | 0.98 | ALDH1A1 (0.45) | — | |
| Purine SCHEMBL619820 | 0.98 | ALDH1A1 (0.45) | — | |
| Purine SCHEMBL712798 | 0.98 | ALDH1A1 (0.45) | — | |
| Purine SCHEMBL31628309 | 0.98 | ALDH1A1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448921-B | Imidazolidine pyrimidinone compounds and use thereof in treatment of HsClpP mediated diseases | 四川大学 | 2023-08-01 | — | — | CN | claimed |
| WO-2023060094-A1 | COMPOSITIONS AND METHODS OF AMELIORATING AVERSIVENESS OF AVERSIVE STIMULI BY INHIBITION OF PURINERGIC RECEPTORS | MONELL CHEMICAL SENSES CENTER (US) | 2023-04-13 | — | — | WO | claimed |
| CN-115515956-A | Benzimidazole derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-12-23 | — | — | CN | claimed |
| CN-114957218-A | Piperidine amine compound containing fused ring pyrimidine and preparation method and application thereof | 沈阳中化农药化工研发有限公司 | 2022-08-30 | — | — | CN | claimed |
| CN-121914109-A | Imidazo pyrimidine compound for targeting TLR7 receptor pathway to treat allergic conjunctivitis, and preparation method and application thereof | 深圳市眼科医院(深圳市眼病防治研究所) | 2026-04-24 | — | — | CN | disclosed |
| CN-121914109-A | Imidazo pyrimidine compound for targeting TLR7 receptor pathway to treat allergic conjunctivitis, and preparation method and application thereof | 深圳市眼科医院(深圳市眼病防治研究所) | 2026-04-24 | — | — | CN | disclosed |
| CN-116789681-B | Imidazo pyrimidine compound containing fused ring group, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2025-09-12 | — | — | CN | disclosed |
| CN-116789681-B | Imidazo pyrimidine compound containing fused ring group, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2025-09-12 | — | — | CN | disclosed |
| WO-2025151620-A1 | FUNCTIONALIZED IMIDAZOPYRIMIDINE COMPOUNDS AND USES THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2025-07-17 | — | — | WO | disclosed |
| WO-2025151620-A1 | FUNCTIONALIZED IMIDAZOPYRIMIDINE COMPOUNDS AND USES THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2025-07-17 | — | — | WO | disclosed |
| CN-120081848-A | Imidazo-containing pyrimidinone derivative, and preparation method and application thereof | 贵州大学 | 2025-06-03 | — | — | CN | disclosed |
| EP-4519268-A1 | SUBSTITUTED IMIDAZOPYRIDINES AND IMIDAZOPYRIMIDINES, AND USE OF SAME FOR TREATING, AMELIORATING, AND/OR PREVENTING RETINAL DEGENERATION | Yale University (US) | 2025-03-12 | — | — | EP | disclosed |
| US-20220242867-A1 | NOVEL IMIDAZOPYRIMIDINE COMPOUNDS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-08-04 | — | — | US | disclosed |
| US-20220242867-A1 | NOVEL IMIDAZOPYRIMIDINE COMPOUNDS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-08-04 | — | — | US | disclosed |
| CN-114728969-A | Pyrimido imidazoles as DNA-PK inhibitors | 南京明德新药研发有限公司 | 2022-07-08 | — | — | CN | disclosed |
| EP-3966215-A1 | SYNTHESIS OF LABELED IMIDAZO[1,2-A]PYRIMIDINES | F. Hoffmann-La Roche AG (CH) | 2022-03-16 | — | — | EP | disclosed |
| EP-3621965-B1 | IMIDAZOPYRIMIDINE DERIVATIVES WITH SULFUR CONTAINING PHENYL AND PYRIDYL SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-02-23 | — | — | EP | disclosed |
| CN-113993870-A | Imidazo pyrimidine compound containing polycyclic group, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-113993870-A | Imidazo pyrimidine compound containing polycyclic group, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-113993870-A | Imidazo pyrimidine compound containing polycyclic group, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2022-01-28 | — | — | CN | disclosed |