SCHEMBL4854900

SCHEMBL4854900

N[C@@H](Cc1cnc(I)[nH]1)C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.54
CYP3A4 P08684 2/20 0.54
SLC1A3 P43003 1/20 0.45
HSD17B10 Q99714 2/20 0.42
PKM P14618 2/20 0.42
ALPI P09923 1/20 0.42
PTGS1 P23219 1/20 0.42
XIAP P98170 1/20 0.42
GRIA2 P42262 3/20 0.40
GRIA1 P42261 2/20 0.40
GRIA4 P48058 2/20 0.40
GRIA3 P42263 1/20 0.40
GRIK5 Q16478 1/20 0.39
USP2 O75604 2/20 0.39
RGS12 O14924 1/20 0.39
CYP2C9 P11712 1/20 0.39
ALOX15 P16050 1/20 0.39
NFKB1 P19838 1/20 0.39
CASP1 P29466 1/20 0.39
BRCA1 P38398 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13095827 0.83 SLC7A5 (0.54) SLC7A5CYP3A4SLC1A3HSD17B10PKM
SCHEMBL59810 0.83 SLC7A5 (0.54) SLC7A5CYP3A4SLC1A3HSD17B10PKM
SCHEMBL59078 0.83 SLC7A5 (0.54) SLC7A5CYP3A4SLC1A3HSD17B10PKM
SCHEMBL5289317 0.83 SLC7A5 (0.54) SLC7A5CYP3A4SLC1A3HSD17B10PKM
SCHEMBL15349978 0.81 SLC7A5 (0.53) SLC7A5CYP3A4SLC1A3HSD17B10PKM
SCHEMBL1065163 0.81 SLC7A5 (0.53) SLC7A5CYP3A4SLC1A3HSD17B10PKM
SCHEMBL5279998 0.81 SLC7A5 (0.53) SLC7A5CYP3A4SLC1A3HSD17B10PKM
SCHEMBL1539194 0.81 SLC7A5 (0.53) SLC7A5CYP3A4SLC1A3HSD17B10PKM
SCHEMBL5292853 0.81 SLC7A5 (0.53) SLC7A5CYP3A4SLC1A3HSD17B10PKM
SCHEMBL11164475 0.81 SLC7A5 (0.53) SLC7A5CYP3A4SLC1A3HSD17B10PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004021981-A2 METHODS FOR THE PREPARATION OF β-AMINO ACIDS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2004-03-18 WO claimed
US-20030113882-A1 Methods for the preparation of beta-amino acids WISCONSIN ALUMNI RESEARCH FOUNDATION 2003-06-19 US claimed
US-7452701-B2 Methods for the preparation of β-amino acids WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2008-11-18 US disclosed
WO-2004021981-A2 METHODS FOR THE PREPARATION OF β-AMINO ACIDS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2004-03-18 WO disclosed
US-20030113882-A1 Methods for the preparation of beta-amino acids WISCONSIN ALUMNI RESEARCH FOUNDATION 2003-06-19 US disclosed
EP-0308983-A2 NMR imaging with Mn(II) coordination compositions SALUTAR, INC. (US) 1989-03-29 EP disclosed