SCHEMBL59810

SCHEMBL59810

Nc1ncc(C[C@H](N)C(=O)O)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.54
CYP3A4 P08684 2/20 0.54
SLC1A3 P43003 1/20 0.45
AOC3 Q16853 1/20 0.45
HSD17B10 Q99714 2/20 0.42
PKM P14618 2/20 0.42
ALPI P09923 1/20 0.42
PTGS1 P23219 1/20 0.42
XIAP P98170 1/20 0.42
GRIA2 P42262 4/20 0.40
GRIA1 P42261 3/20 0.40
GRIA4 P48058 3/20 0.40
GRIA3 P42263 2/20 0.40
GRIK5 Q16478 1/20 0.39
USP2 O75604 2/20 0.39
RGS12 O14924 1/20 0.39
CYP2C9 P11712 1/20 0.39
ALOX15 P16050 1/20 0.39
NFKB1 P19838 1/20 0.39
CASP1 P29466 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13095827 1.00 SLC7A5 (0.54) SLC7A5CYP3A4SLC1A3AOC3HSD17B10
SCHEMBL5289317 1.00 SLC7A5 (0.54) SLC7A5CYP3A4SLC1A3AOC3HSD17B10
SCHEMBL11164475 0.85 SLC7A5 (0.53) SLC7A5CYP3A4SLC1A3HSD17B10PKM
SCHEMBL18071081 0.85 GRIA1 (0.46) SLC7A5CYP3A4SLC1A3AOC3GRIA2
SCHEMBL4854900 0.83 SLC7A5 (0.54) SLC7A5CYP3A4SLC1A3HSD17B10PKM
SCHEMBL59078 0.83 SLC7A5 (0.54) SLC7A5CYP3A4SLC1A3HSD17B10PKM
SCHEMBL15349978 0.81 SLC7A5 (0.53) SLC7A5CYP3A4SLC1A3HSD17B10PKM
SCHEMBL1065163 0.81 SLC7A5 (0.53) SLC7A5CYP3A4SLC1A3HSD17B10PKM
SCHEMBL1539194 0.81 SLC7A5 (0.53) SLC7A5CYP3A4SLC1A3HSD17B10PKM
SCHEMBL5292853 0.81 SLC7A5 (0.53) SLC7A5CYP3A4SLC1A3HSD17B10PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1708 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103499-A1 BIOREVERSABLE PROMOIETIES FOR NITROGEN-CONTAINING AND HYDROXYL-CONTAINING DRUGS HAN JIE (US) 2026-04-16 US claimed
US-20250122239-A1 DUAL AGONIST GLP-1 AND NEUROTENSIN FUSION PEPTIDE HOLST BIRGITTE (DK) 2025-04-17 US claimed
WO-2025069009-A1 ROCK2 INHIBITORS IN THE TREATMENT OF OBESITY GRAVITON BIOSCIENCE BV (NL) 2025-04-03 WO claimed
EP-3891176-B1 DUAL AGONIST GLP-1 AND NEUROTENSIN FUSION PEPTIDE HOLST BIRGITTE (DK) 2024-06-05 EP claimed
CN-117778530-A Method for adding preset joint to 5' end of single-stranded DNA 清华大学 2024-03-29 CN claimed
EP-3250191-B1 TABLETS COMPRISING GLP-1 AGONIST AND ENTERIC COATING NOVO NORDISK AS (DK) 2024-01-17 EP claimed
EP-3077008-B1 BIOREVERSABLE PROMOIETIES FOR NITROGEN-CONTAINING AND HYDROXYL-CONTAINING DRUGS HAN JIE (CN) 2023-10-04 EP claimed
CN-112043835-B Bioreversible introducing group for nitrogen and hydroxyl-containing drugs 韩捷 2022-10-21 CN claimed
EP-2637698-B1 DOUBLE-ACYLATED GLP-1 DERIVATIVES NOVO NORDISK AS (DK) 2022-04-20 EP claimed
US-20220056077-A1 DUAL AGONIST GLP-1 AND NEUROTENSIN FUSION PEPTIDE RATNER, Cecilia (DK) 2022-02-24 US claimed
US-6277819-B1 GLUCAGON LIKE PEPTIDE1 (GLP-1) USED TO NORMALIZE BLOOD GLUCOSE IN DIABETIC PATIENTS ELI LILLY AND COMPANY 2001-08-21 US claimed
EP-1049486-A1 GLP-1 FORMULATIONS ELI LILLY AND COMPANY (US) 2000-11-08 EP claimed
US-6133235-A FOR TREATING MATURITY ONSET DIABETES MELLITUS IN MAMMALS, PARTICULARLY HUMANS ELI LILLY AND COMPANY (US) 2000-10-17 US claimed
US-5981488-A POLYPEPTIDE; ANTIDIABETIC AGENT ELI LILLLY AND COMPANY (US) 1999-11-09 US claimed
US-5977071-A COMPLEXES; ANTIDIABETIC AGENT ELI LILLY AND COMPANY (US) 1999-11-02 US claimed
WO-1999029336-A1 GLP-1 FORMULATIONS ELI LILLY AND COMPANY (US) 1999-06-17 WO claimed
WO-1998043658-A1 GLUCAGON-LIKE PEPTIDE-1 ANALOGS ELI LILLY AND COMPANY (US) 1998-10-08 WO claimed
EP-0869135-A1 Glucagon-like peptide-1 analogs ELI LILLY AND COMPANY (US) 1998-10-07 EP claimed
EP-0733644-A1 Glucagon-like insulinotropic complexes, compositions and methods ELI LILLY AND COMPANY (US) 1996-09-25 EP claimed
CN-1131674-A Glucagon insulinotropic complexes, compositions and methods LILLY CO ELI (US) 1996-09-25 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103499-A1 BIOREVERSABLE PROMOIETIES FOR NITROGEN-CONTAINING AND HYDROXYL-CONTAINING DRUGS CBR1, CBR3, SIGMAR1 SLC7A5 424/4885CYP3A4 59/4885SLC1A3 1837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.