Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14017328 | 1.00 | ALDH1A1 (0.50) | ALDH1A1SIGMAR1MMEKMT2APOLB | |
| SCHEMBL27812225 | 1.00 | ALDH1A1 (0.50) | ALDH1A1SIGMAR1MMEKMT2APOLB | |
| SCHEMBL4855809 | 1.00 | ALDH1A1 (0.50) | ALDH1A1SIGMAR1MMEKMT2APOLB | |
| SCHEMBL2074599 | 0.90 | ALDH1A1 (0.53) | ALDH1A1SIGMAR1MMEKMT2APOLB | |
| SCHEMBL7876545 | 0.90 | ALDH1A1 (0.53) | ALDH1A1SIGMAR1MMEKMT2APOLB | |
| SCHEMBL31336702 | 0.90 | ALDH1A1 (0.53) | ALDH1A1SIGMAR1MMEKMT2APOLB | |
| SCHEMBL7293707 | 0.90 | ALDH1A1 (0.53) | ALDH1A1SIGMAR1MMEKMT2APOLB | |
| SCHEMBL7599136 | 0.90 | ALDH1A1 (0.53) | ALDH1A1SIGMAR1MMEKMT2APOLB | |
| Hydrochloric Acid SCHEMBL28520370 | 0.88 | ALDH1A1 (0.51) | ALDH1A1SIGMAR1MMEKMT2APOLB | |
| SCHEMBL8093317 | 0.84 | ALDH1A1 (0.54) | ALDH1A1SIGMAR1KMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432087-B2 | Method for preparing (2S, 3R, 4S)-4-hydroxyisoleucine and analogues thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFQUE (FR) | 2008-10-07 | — | — | US | disclosed |
| EP-1268397-B1 | METHOD FOR PREPARING (2S,3R,4S)-4-HYDROXYISOLEUCINE AND ANALOGUES THEREOF | CENTRE NAT RECH SCIENT (FR) | 2007-12-05 | — | — | EP | disclosed |
| US-20050079587-A1 | Method for preparing (2S, 3R, 4S) -4-hydroxyisoleucine and analogues thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE | 2005-04-14 | — | — | US | disclosed |
| US-20030219880-A1 | Method for preparing (2s,3r,4s)-4-hydroxyisoleucine and analogues thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2003-11-27 | — | — | US | disclosed |
| EP-1268397-A2 | METHOD FOR PREPARING (2S,3R,4S)-4-HYDROXYISOLEUCINE AND ANALOGUES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001072688-A2 | METHOD FOR PREPARING (2S,3R,4S)-4-HYDROXYISOLEUCINE AND ANALOGUES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2001-10-04 | — | — | WO | disclosed |