Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7599136 | 1.00 | ALDH1A1 (0.53) | ALDH1A1MMESIGMAR1KMT2APOLB | |
| SCHEMBL7293707 | 1.00 | ALDH1A1 (0.53) | ALDH1A1MMESIGMAR1KMT2APOLB | |
| SCHEMBL2074599 | 1.00 | ALDH1A1 (0.53) | ALDH1A1MMESIGMAR1KMT2APOLB | |
| SCHEMBL31336702 | 1.00 | ALDH1A1 (0.53) | ALDH1A1MMESIGMAR1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL28520370 | 0.98 | ALDH1A1 (0.51) | ALDH1A1MMESIGMAR1KMT2APOLB | |
| Phosphoric Acid SCHEMBL28688921 | 0.94 | ACP3 (0.50) | ALDH1A1MMESIGMAR1KMT2APOLB | |
| SCHEMBL400880 | 0.90 | ALDH1A1 (0.56) | ALDH1A1MMEKMT2AMEN1MAPT | |
| SCHEMBL4854909 | 0.90 | ALDH1A1 (0.50) | ALDH1A1MMESIGMAR1KMT2APOLB | |
| SCHEMBL14017328 | 0.90 | ALDH1A1 (0.50) | ALDH1A1MMESIGMAR1KMT2APOLB | |
| SCHEMBL4855809 | 0.90 | ALDH1A1 (0.50) | ALDH1A1MMESIGMAR1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965526-A | FOR DESIGN OF COMPOUNDS HAVING BIOLOGICAL ACTIVITY; FOR INHIBITING BINDING ACTIVITY OF NK2 RECEPTORS | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 1999-10-12 | — | — | US | claimed |
| US-6313095-B1 | HERPES VIRAL RIBONUCLEOTIDE REDUCTASE INHIBITORS | BOEHRINGER INGELHEIM (CANADA), LTD. (CA) | 2001-11-06 | — | — | US | disclosed |
| EP-0411333-B1 | Antiherpes tetrapeptide derivatives having a substituted aspartic acid side chain | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1995-05-31 | — | — | EP | disclosed |
| EP-0383190-A2 | Ribonucleotide reductase inhibitors | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1990-08-22 | — | — | EP | disclosed |
| US-4022760-A | HORMONES | PARKE, DAVIS & COMPANY (US) | 1977-05-10 | — | — | US | disclosed |