SCHEMBL4855064

SCHEMBL4855064

c1ccc2cc3c(cc2c1)Cc1ccc2ccccc2c1-3

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.41
HSD17B10 Q99714 3/20 0.41
TSHR P16473 3/20 0.41
ALDH1A1 P00352 2/20 0.41
CYP2A6 P11509 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
WDR5 P61964 1/20 0.40
HIF1A Q16665 1/20 0.40
CYP1B1 Q16678 1/20 0.40
DNMT1 P26358 1/20 0.39
HPRT1 P00492 1/20 0.38
SOS1 Q07889 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CYP3A4 P08684 2/20 0.36
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 1/20 0.36
TP53 P04637 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4852483 0.91 HPRT1 (0.48) MAPTHSD17B10TSHRALDH1A1CYP2A6
SCHEMBL4854059 0.87 TSHR (0.39) MAPTHSD17B10TSHRALDH1A1CYP2A6
SCHEMBL14452865 0.86 CLK1 (0.43) MAPTALDH1A1KDM4EGPR84ALOX5
SCHEMBL14452842 0.86 CLK1 (0.43) MAPTALDH1A1KDM4EGPR84ALOX5
SCHEMBL29716676 0.83 TSHR (0.52) MAPTHSD17B10TSHRALDH1A1CYP2A6
SCHEMBL868639 0.83 TSHR (0.52) MAPTHSD17B10TSHRALDH1A1CYP2A6
SCHEMBL867598 0.82 DNMT1 (0.44) MAPTHSD17B10TSHRALDH1A1CYP2A6
SCHEMBL29520144 0.82 DNMT1 (0.44) MAPTHSD17B10TSHRALDH1A1CYP2A6
SCHEMBL21385140 0.81 TSHR (0.50) MAPTHSD17B10TSHRALDH1A1CYP2A6
SCHEMBL19152708 0.79 CA1 (0.48) HSD17B10TSHRALDH1A1CYP2A6TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11555028-B2 Organic compound and photoelectric conversion element CANON KABUSHIKI KAISHA (JP) 2023-01-17 US disclosed
US-20190119258-A1 ORGANIC COMPOUND AND PHOTOELECTRIC CONVERSION ELEMENT CANON KABUSHIKI KAISHA (JP) 2019-04-25 US disclosed
US-7470290-B2 Hydroscopic polymer gels for easier cleaning THE CLOROX COMPANY (US) 2008-12-30 US disclosed
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 US disclosed
US-20050245428-A1 Hydroscopic polymer gels for easier cleaning RODRIGUES KLIN A 2005-11-03 US disclosed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190119258-A1 ORGANIC COMPOUND AND PHOTOELECTRIC CONVERSION ELEMENT SCN2B, MRPS22, CTNNA1 MAPT 3956/4885HSD17B10 1632/4885TSHR 3018/4885
US-11555028-B2 Organic compound and photoelectric conversion element SCN2B, MRPS22, CTNNA1 MAPT 3956/4885HSD17B10 1632/4885TSHR 3018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.