SCHEMBL867598

SCHEMBL867598

c1ccc2c(c1)Cc1ccc3ccccc3c1-2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.44
MAOA P21397 1/20 0.43
TSHR P16473 3/20 0.42
ALDH1A1 P00352 3/20 0.42
HSD17B10 Q99714 3/20 0.42
CYP2A6 P11509 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MAPT P10636 3/20 0.41
KDM4E B2RXH2 2/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
LMNA P02545 1/20 0.41
HPGD P15428 1/20 0.41
CYP3A4 P08684 2/20 0.41
MEN1 O00255 1/20 0.41
TP53 P04637 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29520144 1.00 DNMT1 (0.44) DNMT1MAOATSHRALDH1A1HSD17B10
SCHEMBL4847777 0.91 HPRT1 (0.50) DNMT1MAOATSHRALDH1A1HSD17B10
SCHEMBL4852791 0.87 TSHR (0.45) DNMT1MAOATSHRALDH1A1HSD17B10
SCHEMBL4845466 0.85 TSHR (0.53) DNMT1MAOATSHRALDH1A1HSD17B10
SCHEMBL30944691 0.85 TSHR (0.53) DNMT1MAOATSHRALDH1A1HSD17B10
SCHEMBL23839 0.85 MAOA (0.57) DNMT1MAOAALDH1A1MAPTKDM4E
SCHEMBL29716676 0.85 TSHR (0.52) DNMT1TSHRALDH1A1HSD17B10CYP2A6
SCHEMBL868639 0.85 TSHR (0.52) DNMT1TSHRALDH1A1HSD17B10CYP2A6
SCHEMBL16114881 0.84 DNMT1 (0.44) DNMT1TSHRALDH1A1HSD17B10CYP2A6
SCHEMBL4852509 0.83 ALDH1A1 (0.42) MAOATSHRALDH1A1HSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 334 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250243389-A1 COMPOSITION COMPRISING ADDITIVE HAVING A POLYCYCLIC AROMATIC GROUP E INK CORPORATION 2025-07-31 US claimed
EP-4557969-A1 FLAVORING COMPOSITIONS HAVING A ROAST AROMA PROFILE Firmenich SA (CH) 2025-05-28 EP claimed
US-12206087-B2 Chemical prealkaliation of electrodes UWM RESEARCH FOUNDATION, INC. (US) 2025-01-21 US claimed
EP-4444905-A2 NANOELECTRIC DEVICES AND USE THEREOF Twist Bioscience Corporation (US) 2024-10-16 EP claimed
WO-2024115460-A1 BINAPHTHYL COMPOUNDS AND THERMOPLASTIC RESINS REUTER CHEMISCHE APPARATEBAU E.K. (DE) 2024-06-06 WO claimed
US-20240164422-A1 FLAVORING COMPOSITIONS FIRMENICH SA (CH) 2024-05-23 US claimed
EP-3857635-B1 CHEMICAL PREALKALIATION OF ELECTRODES UWM RES FOUNDATION INC (US) 2024-04-10 EP claimed
WO-2024068860-A1 OLIGOMERIC BINAPHTYL COMPOUNDS AND THERMOPLASTIC RESINS REUTER CHEMISCHE APPARATEBAU E.K. (DE) 2024-04-04 WO claimed
WO-2024061741-A1 FLAVORING COMPOSITIONS HAVING A ROAST AROMA PROFILE FIRMENICH SA (CH) 2024-03-28 WO claimed
CN-111479870-B Interpenetrating elastomer network derived from ground tire rubber particles 威廉·B·克 2024-03-19 CN claimed
CN-111707767-A Method for measuring polycyclic aromatic hydrocarbon in tobacco, main stream smoke or heated non-burning cigarette 国家烟草质量监督检验中心 2020-09-25 CN claimed
CN-108344831-B Method for measuring polycyclic aromatic hydrocarbon in tobacco, main stream smoke or heated non-burning cigarette 国家烟草质量监督检验中心 2020-08-25 CN claimed
CN-111562334-A Method for detecting polycyclic aromatic hydrocarbon residue in plant traditional Chinese medicinal materials and extracts 劲牌有限公司 2020-08-21 CN claimed
EP-2006278-B1 BENZOFLUORENE COMPOUND AND USE THEREOF TOSOH CORP (JP) 2012-12-26 EP claimed
US-20120074336-A1 LIGHT-DRIVEN ROTARY MOLECULAR MOTORS BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE (US) 2012-03-29 US claimed
US-7964722-B2 Light-driven rotary molecular motors BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) 2011-06-21 US claimed
US-20110077394-A1 LIGHT-DRIVEN ROTARY MOLECULAR MOTORS NATIONAL SCIENCE FOUNDATION 2011-03-31 US claimed
EP-2006278-A9 BENZOFLUORENE COMPOUND AND USE THEREOF Tosoh Corporation (JP) 2009-08-05 EP claimed
US-20090184312-A1 BENZOFLUORENE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2009-07-23 US claimed
EP-2006278-A2 BENZOFLUORENE COMPOUND AND USE THEREOF Tosoh Corporation (JP) 2008-12-24 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090184312-A1 BENZOFLUORENE COMPOUND AND USE THEREOF SLC7A1, SLC43A1, SLC7A5 DNMT1 4199/4885MAOA 4169/4885TSHR 3118/4885
US-20110077394-A1 LIGHT-DRIVEN ROTARY MOLECULAR MOTORS CCNA2, CCNO, SCO2 DNMT1 1555/4885MAOA 3251/4885TSHR 752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.