SCHEMBL4855313

SCHEMBL4855313

c1ccc2c(c1)Cc1c-2ccc2ccc3ccccc3c12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
PNMT P11086 1/20 0.42
TSHR P16473 2/20 0.41
CYP3A4 P08684 1/20 0.41
BCHE P06276 1/20 0.41
ACHE P22303 1/20 0.41
ALDH1A1 P00352 4/20 0.38
HSD17B10 Q99714 2/20 0.38
CYP2A6 P11509 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
HTR7 P34969 4/20 0.38
HPGD P15428 3/20 0.38
KDM4E B2RXH2 2/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
HTR2B P41595 2/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22645278 0.88 CA1 (0.39) CA1CA2CA4CA6PNMT
Benzo(A)Fluorene SCHEMBL150250 0.87 CA1 (0.46) CA1CA2CA4CA6PNMT
Benzo(A)Fluorene SCHEMBL29432662 0.87 CA1 (0.46) CA1CA2CA4CA6PNMT
Benzo(A)Fluorene SCHEMBL29413802 0.87 CA1 (0.46) CA1CA2CA4CA6PNMT
Benzo(A)Fluorene SCHEMBL29620372 0.87 CA1 (0.46) CA1CA2CA4CA6PNMT
Benzo(A)Fluorene SCHEMBL27981434 0.85 CA1 (0.44) CA1CA2CA4CA6PNMT
SCHEMBL27934827 0.82 HPRT1 (0.50) CA1CA2CA4CA6PNMT
SCHEMBL31199126 0.82 HPRT1 (0.50) CA1CA2CA4CA6PNMT
SCHEMBL2486633 0.82 HPRT1 (0.50) CA1CA2CA4CA6PNMT
SCHEMBL4852395 0.81 ALDH1A1 (0.49) CA1CA2CA4CA6PNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7470290-B2 Hydroscopic polymer gels for easier cleaning THE CLOROX COMPANY (US) 2008-12-30 US disclosed
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 US disclosed
US-20050245428-A1 Hydroscopic polymer gels for easier cleaning RODRIGUES KLIN A 2005-11-03 US disclosed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US disclosed
EP-0832882-B1 Naphthofluorene compounds, intermediates, compositions, and methods LILLY CO ELI (US) 2002-04-03 EP disclosed
EP-0832882-A2 Naphthofluorene compounds, intermediates, compositions, and methods ELI LILLY AND COMPANY (US) 1998-04-01 EP disclosed