Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11342153 | 0.75 | MAPK1 (0.44) | MAPK1TSHRCYP2C19HIF1AALDH1A1 | |
| SCHEMBL705506 | 0.75 | MAPK1 (0.44) | MAPK1TSHRCYP2C19HIF1AALDH1A1 | |
| SCHEMBL22730252 | 0.71 | MAPK1 (0.41) | MAPK1TSHRCYP2C19HIF1AALDH1A1 | |
| SCHEMBL6892052 | 0.70 | TSHR (0.44) | MAPK1TSHRCYP2C19HIF1AALDH1A1 | |
| SCHEMBL5167778 | 0.69 | TSHR (0.48) | MAPK1TSHRCYP2C19HIF1AALDH1A1 | |
| SCHEMBL10448326 | 0.68 | CYP2C19 (0.41) | MAPK1TSHRCYP2C19HIF1AALDH1A1 | |
| Tert-Butylbenzene SCHEMBL28464198 | 0.68 | TSHR (0.53) | MAPK1TSHRCYP2C19HIF1AALDH1A1 | |
| Tert-Butylbenzene SCHEMBL27713888 | 0.68 | TSHR (0.53) | MAPK1TSHRCYP2C19HIF1AALDH1A1 | |
| SCHEMBL10824244 | 0.67 | TSHR (0.52) | MAPK1TSHRCYP2C19HIF1AALDH1A1 | |
| SCHEMBL15275694 | 0.67 | TSHR (0.52) | MAPK1TSHRCYP2C19HIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9562113-B2 | Labeled alginate conjugates for molecular imaging applications | BELLEROPHON BCM LLC (US) | 2017-02-07 | — | — | US | disclosed |
| US-20160115252-A1 | Labeled Alginate Conjugates For Molecular Imaging Applications | IKARIA DEVELOPMENT SUBSIDIARY ONE LLC | 2016-04-28 | — | — | US | disclosed |
| US-9260399-B2 | Labeled alginate conjugates for molecular imaging applications | BELLEROPHON BCM LLC (US) | 2016-02-16 | — | — | US | disclosed |
| US-20150133645-A1 | Labeled Alginate Conjugates For Molecular Imaging Applications | IKARIA DEVELOPMENT SUBSIDIARY ONE LLC | 2015-05-14 | — | — | US | disclosed |
| US-8974766-B2 | Labeled alginate conjugates for molecular imaging applications | BELLEROPHON BCM LLC (US) | 2015-03-10 | — | — | US | disclosed |
| US-20130149242-A1 | Labeled Alginate Conjugates for Molecular Imaging Applications | IKARIA DEVELOPMENT SUBSIDIARY ONE LLC (US) | 2013-06-13 | — | — | US | disclosed |
| US-7368578-B2 | Five-membered heterocyclic compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-06 | — | — | US | disclosed |
| US-20060135578-A1 | Five-membered heterocyclic compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-06-22 | — | — | US | disclosed |
| EP-1541564-A1 | FIVE-MEMBERED HETEROCYCLIC COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2005-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160115252-A1 | Labeled Alginate Conjugates For Molecular Imaging Applications | ALG1, ALG8, ALG3 | MAPK1 4661/4885TSHR 4161/4885CYP2C19 4858/4885 |
| US-20150133645-A1 | Labeled Alginate Conjugates For Molecular Imaging Applications | ALG1, ALG8, ALG3 | MAPK1 4661/4885TSHR 4161/4885CYP2C19 4858/4885 |
| US-20130149242-A1 | Labeled Alginate Conjugates for Molecular Imaging Applications | ALG1, ALG8, ALG3 | MAPK1 4661/4885TSHR 4161/4885CYP2C19 4858/4885 |
| US-20060135578-A1 | Five-membered heterocyclic compounds | GPR119, OR10J3, CYP11B1 | MAPK1 1445/4885TSHR 2067/4885CYP2C19 446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.