SCHEMBL4856417

SCHEMBL4856417

C=CCN(CC=C)c1ncnc(Cl)n1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 2/20 0.33
ALDH1A1 P00352 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11806550 0.82 ALDH1A1 (0.36) ALDH1A1L3MBTL1
SCHEMBL9821919 0.78 CRHR1 (0.37) CRHR1ALDH1A1
SCHEMBL9821986 0.78 CRHR1 (0.37) CRHR1ALDH1A1
SCHEMBL24727888 0.78 ADORA2A (0.40) CRHR1ALDH1A1
SCHEMBL9507522 0.78 CRHR1 (0.33) CRHR1
SCHEMBL24728110 0.78 CRHR1 (0.33) CRHR1
SCHEMBL1323657 0.75 TDP1 (0.45) ALDH1A1
SCHEMBL1555113 0.74 TAAR1 (0.35) CRHR1
SCHEMBL369673 0.74 CRHR1 (0.34) CRHR1
SCHEMBL8018201 0.74 CRHR1 (0.34) CRHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008072850-A1 TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE AMOREPACIFIC CORPORATION (KR) 2008-06-19 WO disclosed
US-5368778-A Cleaner for thermostatic water bath WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1994-11-29 US disclosed
EP-0347815-B1 CLEANER FOR THERMOSTATIC WATER BATH SAN-AI OIL CO., LTD. (JP) 1993-09-01 EP disclosed
US-5238936-A Antitumor agents, anticarcinogenic agents ADIR ET COMPAGNIE (FR) 1993-08-24 US disclosed
US-5230811-A Mixture of triazine compound, surfactant and hydroxyamine compound SHIMOTOMAI NAOMASA (JP) 1993-07-27 US disclosed
US-5225411-A Triazines ADIR ET COMPAGNIE (FR) 1993-07-06 US disclosed
EP-0502788-A1 Trisubstituted triazines and pyrimidines, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1992-09-09 EP disclosed
EP-0347815-A2 Cleaner for thermostatic water bath SAN-AI OIL CO., LTD. (JP) 1989-12-27 EP disclosed
EP-0101411-B1 PROCESS FOR THE CHEMICAL BOND BETWEEN A STABILISING COMPOUND AND A POLYMER CIBA-GEIGY AG (CH) 1989-01-25 EP disclosed
EP-0070386-B1 NOVEL LIGHT STABILIZERS FOR POLYMERS AMERICAN CYANAMID COMPANY (US) 1989-01-11 EP disclosed
US-4731393-A TRIAZINYL DERIVATIVES OF PIPERIDINE CIBA-GEIGY CORPORATION (US) 1988-03-15 US disclosed
US-4461861-A Polymer compositions stabilized with triazinyl-piperidine compounds AMERICAN CYANAMID COMPANY (US) 1984-07-24 US disclosed
US-4415658-A EFFLUENTS CONTAINING HERBICIDE BY-PRODUCTS TREATED AEROBICALLY WITH PSEUDOMONAS CIBA-GEIGY CORPORATION (US) 1983-11-15 US disclosed
US-4400505-A Triazinyl-piperidines as light stabilizers for polymers AMERICAN CYANAMID COMPANY (US) 1983-08-23 US disclosed
EP-0070386-A1 Novel light stabilizers for polymers AMERICAN CYANAMID COMPANY (US) 1983-01-26 EP disclosed
US-4288594-A Caustic-free process for the production of monochloro-diamino-s-triazines CIBA-GEIGY CORPORATION (US) 1981-09-08 US disclosed
US-4274955-A BIODEGRADATION WITH SPOROTHRIX FUNGI CIBA-GEIGY CORPORATION (US) 1981-06-23 US disclosed
US-4058662-A Process for the substitution of chlorine atoms of cyanuric chloride DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1977-11-15 US disclosed
US-4054739-A Process for the substitution of chlorine atoms of cyanuric chloride DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1977-10-18 US disclosed