Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM3 | Q86V86 | 3/20 | 0.62 |
| ▸ | PIM1 | P11309 | 2/20 | 0.62 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | AHR | P35869 | 2/20 | 0.58 |
| ▸ | KIF11 | P52732 | 7/20 | 0.49 |
| ▸ | GABRP | O00591 | 2/20 | 0.47 |
| ▸ | GABRD | O14764 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.47 |
| ▸ | GABRE | P78334 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30568791 | 1.00 | PIM3 (0.62) | PIM3PIM1PIM2MEN1MAPT | |
| SCHEMBL27574548 | 0.89 | MEN1 (0.54) | PIM3PIM1PIM2MEN1MAPT | |
| SCHEMBL2253358 | 0.80 | PIM1 (0.63) | PIM3PIM1PIM2MEN1MAPT | |
| SCHEMBL29603193 | 0.80 | PIM1 (0.63) | PIM3PIM1PIM2MEN1MAPT | |
| SCHEMBL4582415 | 0.79 | MEN1 (0.54) | PIM3PIM1PIM2MEN1MAPT | |
| SCHEMBL4582412 | 0.79 | PIM1 (0.57) | PIM3PIM1PIM2MEN1MAPT | |
| SCHEMBL647469 | 0.79 | MAPT (0.54) | PIM3PIM1PIM2MEN1MAPT | |
| SCHEMBL28193668 | 0.78 | PIM3 (0.56) | PIM3PIM1PIM2MEN1MAPT | |
| SCHEMBL1290995 | 0.77 | PIM3 (0.59) | PIM3PIM1PIM2MEN1MAPT | |
| SCHEMBL844764 | 0.77 | PIM3 (1.00) | PIM3PIM1PIM2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101993432-A | Carbazoles chalcone derivatives based on carbazole and preparation method thereof | UNIV SOUTHWEST | 2011-03-30 | — | — | CN | claimed |
| CN-101993432-B | Carbazoles chalcone derivatives based on carbazole and preparation method thereof | UNIV SOUTHWEST | 2014-05-07 | — | — | CN | disclosed |
| CN-101993432-A | Carbazoles chalcone derivatives based on carbazole and preparation method thereof | UNIV SOUTHWEST | 2011-03-30 | — | — | CN | disclosed |
| US-7432028-B2 | Polymeric charge transport compositions | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-10-07 | — | — | US | disclosed |
| US-6864025-B2 | Sulfonyldiphenylene-based charge transport compositions | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2005-03-08 | — | — | US | disclosed |
| US-6835513-B2 | An organophotoreceptor comprising: (a) a charge transport compound having the formula carbazole compound dispersion of colorant particles in an organic liquid and charge transport compound having the formula of carbazole compound | SAMSUNG ELECTRONIC CO., LTD. (KR) | 2004-12-28 | — | — | US | disclosed |
| EP-1471391-A1 | Polymeric charge transport compositions | Samsung Electronics Co., Ltd. (KR) | 2004-10-27 | — | — | EP | disclosed |
| US-20040191655-A1 | Polymeric charge transport compositions | S-PRINTING SOLUTION CO., LTD. (KR) | 2004-09-30 | — | — | US | disclosed |
| US-20030207188-A1 | Carbazole based charge transport compounds | S-PRINTING SOLUTION CO., LTD. (KR) | 2003-11-06 | — | — | US | disclosed |
| US-20030203296-A1 | Sulfonyldiphenylene-based charge transport compositions | S-PRINTING SOLUTION CO., LTD. (KR) | 2003-10-30 | — | — | US | disclosed |
| US-6503998-B2 | Nonlinear Optical (nlo) materials, sulfon-diol-ether derivatives | NATIONAL SCIENCE COUNCIL (TW) | 2003-01-07 | — | — | US | disclosed |
| US-5807974-A | POLYARYLENEVINYLENE RESIN | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1998-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207188-A1 | Carbazole based charge transport compounds | SLC33A1, SLC43A1, AHR | PIM3 3353/4885PIM1 3663/4885PIM2 3990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.