SCHEMBL4582415

SCHEMBL4582415

O=Cc1c(-c2ccccc2)ccc2c1[nH]c1ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.54
MAPT P10636 2/20 0.54
KMT2A Q03164 2/20 0.54
AHR P35869 1/20 0.54
PIM1 P11309 1/20 0.50
PIM3 Q86V86 1/20 0.50
PIM2 Q9P1W9 1/20 0.50
HPGD P15428 2/20 0.46
MAPK1 P28482 2/20 0.46
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TDO2 P48775 2/20 0.45
HTR2B P41595 1/20 0.45
HTR5A P47898 1/20 0.45
KIF11 P52732 5/20 0.45
GABRP O00591 2/20 0.44
GABRD O14764 2/20 0.44
GABRA1 P14867 2/20 0.44
GABRB1 P18505 2/20 0.44
GABRG2 P18507 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28172630 0.84 TDO2 (0.45) MEN1MAPTKMT2AAHRPIM1
SCHEMBL28118998 0.83 MEN1 (0.60) MEN1MAPTKMT2AAHRPIM1
SCHEMBL30568791 0.79 PIM3 (0.62) MEN1MAPTKMT2AAHRPIM1
SCHEMBL4856734 0.79 PIM3 (0.62) MEN1MAPTKMT2AAHRPIM1
SCHEMBL30958714 0.78 PIM1 (0.43) MEN1MAPTKMT2AAHRPIM1
SCHEMBL30022621 0.77 ESR1 (0.52) MAPTHPGDMAPK1HTTSMN1; SMN2
SCHEMBL193017 0.77 ESR1 (0.52) MAPTHPGDMAPK1HTTSMN1; SMN2
SCHEMBL17061024 0.76 ESR1 (0.50) MAPTHPGDMAPK1HTTSMN1; SMN2
Ammonia Solution, Strong SCHEMBL14343305 0.76 ESR1 (0.50) MAPTHPGDMAPK1HTTSMN1; SMN2
SCHEMBL16337986 0.76 TDO2 (0.49) MEN1MAPTKMT2APIM1PIM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1621929-B1 Photosensitive composition comprising a sensitising dye FUJIFILM CORP (JP) 2012-10-31 EP disclosed
US-7396634-B2 Photosensitive composition FUJIFILM CORPORATION (JP) 2008-07-08 US disclosed
US-20060073410-A1 Photosensitive composition FUJI PHOTO FILM CO., LTD. 2006-04-06 US disclosed
EP-1621929-A2 Photosensitive composition comprising a sensitising dye Fuji Photo Film Co., Ltd. (JP) 2006-02-01 EP disclosed