Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 6/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 6/20 | 0.44 |
| ▸ | NOS3 | P29474 | 2/20 | 0.44 |
| ▸ | NOS1 | P29475 | 2/20 | 0.44 |
| ▸ | NOS2 | P35228 | 2/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 5/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.36 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.36 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucine SCHEMBL28204697 | 0.72 | SLC7A5 (0.82) | SLC7A5SLC1A3SLC1A2SLC1A1NOS3 | |
| SCHEMBL3059628 | 0.70 | — | — | |
| SCHEMBL20107156 | 0.70 | NOS3 (0.54) | SLC7A5SLC1A3SLC1A2SLC1A1NOS3 | |
| Leucine SCHEMBL8951304 | 0.69 | SLC7A5 (0.75) | SLC7A5SLC1A3SLC1A2SLC1A1NOS3 | |
| Leucine SCHEMBL30257452 | 0.69 | SLC7A5 (0.95) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| SCHEMBL3069002 | 0.69 | ALOX5 (0.32) | NOS3NOS1NOS2 | |
| Leucine SCHEMBL998945 | 0.68 | SLC7A5 (0.90) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| Leucine SCHEMBL998944 | 0.68 | SLC7A5 (0.90) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| SCHEMBL18528337 | 0.68 | NOS3 (0.37) | SLC7A5NOS3NOS1NOS2 | |
| Leucine SCHEMBL25241602 | 0.67 | SLC7A5 (1.00) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004021981-A2 | METHODS FOR THE PREPARATION OF β-AMINO ACIDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2004-03-18 | — | — | WO | claimed |
| US-20030113882-A1 | Methods for the preparation of beta-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2003-06-19 | — | — | US | claimed |
| US-7452701-B2 | Methods for the preparation of β-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-11-18 | — | — | US | disclosed |
| WO-2004021981-A2 | METHODS FOR THE PREPARATION OF β-AMINO ACIDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2004-03-18 | — | — | WO | disclosed |
| US-20030113882-A1 | Methods for the preparation of beta-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2003-06-19 | — | — | US | disclosed |