SCHEMBL4858092

SCHEMBL4858092

CCCCCC(C=O)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.41
SIGMAR1 Q99720 1/20 0.41
POLB P06746 1/20 0.41
CNR2 P34972 1/20 0.41
LMNA P02545 1/20 0.40
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 1/20 0.40
HTR2A P28223 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TACR3 P29371 1/20 0.39
ASAH1 Q13510 2/20 0.39
OPRM1 P35372 1/20 0.38
OPRD1 P41143 1/20 0.38
OPRK1 P41145 1/20 0.38
OPRL1 P41146 1/20 0.38
CSNK1E P49674 1/20 0.38
ACER2 Q5QJU3 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9340451 0.98 NAAA (0.43) NAAASIGMAR1POLBCNR2ALDH1A1
SCHEMBL22471817 0.98 NAAA (0.43) NAAASIGMAR1POLBCNR2ALDH1A1
SCHEMBL8357721 0.98 NAAA (0.43) NAAASIGMAR1POLBCNR2ALDH1A1
SCHEMBL8351977 0.98 NAAA (0.43) NAAASIGMAR1POLBCNR2ALDH1A1
SCHEMBL8352391 0.98 NAAA (0.43) NAAASIGMAR1POLBCNR2ALDH1A1
SCHEMBL25273765 0.98 NAAA (0.43) NAAASIGMAR1POLBCNR2ALDH1A1
SCHEMBL22471869 0.98 NAAA (0.43) NAAASIGMAR1POLBCNR2ALDH1A1
SCHEMBL22471827 0.98 NAAA (0.43) NAAASIGMAR1POLBCNR2ALDH1A1
SCHEMBL22471836 0.98 NAAA (0.43) NAAASIGMAR1POLBCNR2ALDH1A1
SCHEMBL7129264 0.94 POLB (0.45) NAAAPOLBCNR2ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116425705-B Application of solvent for co-production of maleic anhydride and succinic anhydride 上海师范大学 2025-06-17 CN claimed
CN-113045519-B Solvent capable of simultaneously meeting production requirements of maleic anhydride and succinic anhydride and application thereof 上海师范大学 2023-05-16 CN claimed
CN-113045519-A Solvent capable of meeting production requirements of maleic anhydride and succinic anhydride simultaneously and application thereof 上海师范大学 2021-06-29 CN claimed
EP-2481760-B1 INITIATOR SYSTEM FOR CATIONIC POLYMERIZATION AND POLYMERIZATION METHOD USING SAME CHINA PETROLEUM & CHEM CORP (CN) 2021-05-05 EP claimed
EP-0606642-B1 Photosensitive recording element and method for the production of a relief printing plate BASF LACKE & FARBEN (DE) 1996-03-13 EP claimed
CN-118852036-A Desulfurizing agent and preparation method and application thereof 南京洛德斯通工程技术有限公司 2024-10-29 CN disclosed
CN-116033834-A Flavor composition for improving taste impression 西姆莱斯有限公司 2023-04-28 CN disclosed
CN-113045519-A Solvent capable of meeting production requirements of maleic anhydride and succinic anhydride simultaneously and application thereof 上海师范大学 2021-06-29 CN disclosed
EP-2481759-B1 ISO-OLEFIN POLYMER AND PREPARATION METHOD THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2021-05-05 EP disclosed
EP-2481760-B1 INITIATOR SYSTEM FOR CATIONIC POLYMERIZATION AND POLYMERIZATION METHOD USING SAME CHINA PETROLEUM & CHEM CORP (CN) 2021-05-05 EP disclosed
US-8937138-B2 Initiating system for cationic polymerization and polymerization process CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2015-01-20 US disclosed
US-8883943-B2 Isoolefin polymers and process for preparing the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2014-11-11 US disclosed
US-20050245554-A1 Substituted pyrimidines MERCK SHARP & DOHME CORP. 2005-11-03 US disclosed
US-20050182103-A1 Substituted 2,3-diphenyl pyridines MERCK SHARP & DOHME CORP. 2005-08-18 US disclosed
EP-1546115-A2 SUBSTITUTED PYRIMIDINES Merck & Co., Inc. (US) 2005-06-29 EP disclosed
EP-1492784-A2 SUBSTITUTED 2,3-DIPHENYL PYRIDINES Merck & Co., Inc. (US) 2005-01-05 EP disclosed
WO-2004029204-A2 SUBSTITUTED PYRIMIDINES MERCK & CO., INC. (US) 2004-04-08 WO disclosed
WO-2003082191-A2 SUBSTITUTED 2,3-DIPHENYL PYRIDINES MERCK & CO., INC. (US) 2003-10-09 WO disclosed
EP-0606642-B1 Photosensitive recording element and method for the production of a relief printing plate BASF LACKE & FARBEN (DE) 1996-03-13 EP disclosed
US-3959226-A ISOMERIZATION; FRIEDEL-CRAFTS CATALYST UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050182103-A1 Substituted 2,3-diphenyl pyridines CNR1, CNR2, MAG NAAA 908/4885SIGMAR1 1160/4885POLB 2320/4885
US-20050245554-A1 Substituted pyrimidines CNR1, CNR2, GPR119 NAAA 831/4885SIGMAR1 1071/4885POLB 441/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.