Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 15/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL662397 | 0.85 | F2R (0.67) | F2R | |
| SCHEMBL486096 | 0.82 | F2R (0.78) | F2RPIK3CD | |
| SCHEMBL486466 | 0.81 | F2R (0.69) | F2RNPC1MAPTSTAT1RAB9A | |
| SCHEMBL485888 | 0.80 | F2R (0.65) | F2RNPC1MAPTSTAT1RAB9A | |
| SCHEMBL485838 | 0.79 | F2R (0.61) | F2R | |
| SCHEMBL486104 | 0.79 | F2R (0.61) | F2RMAPTRAB9A | |
| SCHEMBL662897 | 0.78 | F2R (0.81) | F2RNPC1MAPTSTAT1RAB9A | |
| SCHEMBL485980 | 0.77 | F2R (0.73) | F2RNPC1MAPTSTAT1RAB9A | |
| SCHEMBL662549 | 0.77 | F2R (0.74) | F2RNPC1MAPTSTAT1RAB9A | |
| SCHEMBL486133 | 0.77 | F2R (1.00) | F2RNPC1MAPTSTAT1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411363-B1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | BAYER IP GMBH (DE) | 2015-10-07 | — | — | EP | disclosed |
| EP-2411363-A1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | Bayer Pharma AG (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108608-A1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-09-30 | — | — | WO | disclosed |