Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 14/20 | 0.61 |
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL662110 | 0.85 | F2R (0.64) | F2RMAPT | |
| SCHEMBL485888 | 0.82 | F2R (0.65) | F2RMEN1RAB9AKMT2AMAPT | |
| SCHEMBL486466 | 0.80 | F2R (0.69) | F2RMEN1RAB9AKMT2AMAPT | |
| SCHEMBL485844 | 0.79 | F2R (0.61) | F2RRAB9AMAPT | |
| SCHEMBL485838 | 0.78 | F2R (0.61) | F2RFAAH | |
| SCHEMBL662897 | 0.78 | F2R (0.81) | F2RMEN1RAB9AKMT2AMAPT | |
| SCHEMBL485980 | 0.76 | F2R (0.73) | F2RMEN1RAB9AKMT2AMAPT | |
| SCHEMBL662549 | 0.76 | F2R (0.74) | F2RRAB9AKMT2AMAPT | |
| SCHEMBL486133 | 0.76 | F2R (1.00) | F2RRAB9AMAPT | |
| SCHEMBL662802 | 0.75 | F2R (0.67) | F2RMEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411363-B1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | BAYER IP GMBH (DE) | 2015-10-07 | — | — | EP | disclosed |
| EP-2411363-A1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | Bayer Pharma AG (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108608-A1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-09-30 | — | — | WO | disclosed |