Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MITF | O75030 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4877523 | 0.88 | KMT2A (0.43) | HRH3KMT2AMEN1MITFRAB9A | |
| SCHEMBL13609978 | 0.86 | HRH3 (0.45) | HRH3KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL27656287 | 0.82 | HRH3 (0.42) | HRH3KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL14204509 | 0.82 | HRH3 (0.42) | HRH3KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL26767784 | 0.82 | HRH3 (0.42) | HRH3KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL24869964 | 0.82 | HRH3 (0.42) | HRH3KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL12698815 | 0.82 | HRH3 (0.42) | HRH3KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL21164045 | 0.82 | HRH3 (0.42) | HRH3KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL22877461 | 0.82 | HRH3 (0.42) | HRH3KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL27774249 | 0.81 | HRH3 (0.48) | HRH3SMN1; SMN2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1991221-A2 | METHODS FOR INCREASING BLOOD FLOW AND/OR PROMOTING TISSUE REGENERATION | Genzyme Corporation (US) | 2008-11-19 | — | — | EP | disclosed |
| WO-2007106063-A2 | METHODS FOR INCREASING BLOOD FLOW AND/OR PROMOTING TISSUE REGENERATION | GENZYME CORPORATION (US) | 2007-09-20 | — | — | WO | disclosed |