Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MITF | O75030 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4858545 | 0.88 | HRH3 (0.42) | KMT2AMEN1MITFRAB9ASMN1; SMN2 | |
| SCHEMBL3302667 | 0.84 | SLC6A3 (0.38) | SLC6A4HRH3SLC6A3SLC6A2 | |
| SCHEMBL898138 | 0.82 | SLC6A3 (0.39) | SLC6A4HRH3SLC6A3SLC6A2 | |
| SCHEMBL23866055 | 0.80 | SLC6A3 (0.36) | SLC6A4HRH3SLC6A3SLC6A2 | |
| SCHEMBL3300015 | 0.80 | SLC6A3 (0.36) | SLC6A4HRH3SLC6A3SLC6A2 | |
| SCHEMBL23733432 | 0.80 | SLC6A3 (0.36) | SLC6A4HRH3SLC6A3SLC6A2 | |
| Iodide SCHEMBL15008876 | 0.80 | SLC6A3 (0.38) | SLC6A4HRH3SLC6A3SLC6A2 | |
| Iodide SCHEMBL10559193 | 0.78 | SLC6A3 (0.35) | SLC6A4HRH3SLC6A3SLC6A2 | |
| Ammonia Solution, Strong SCHEMBL464958 | 0.78 | SLC6A3 (0.35) | SLC6A4HRH3SLC6A3SLC6A2 | |
| Bromide SCHEMBL11218003 | 0.78 | SLC6A3 (0.35) | SLC6A4HRH3SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3720494-A2 | DOSING REGIMENS FOR THE MOBILIZATION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS | Magenta Therapeutics, Inc. (US) | 2020-10-14 | — | — | EP | disclosed |
| WO-2019113375-A2 | DOSING REGIMENS FOR THE MOBILIZATION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS | Magenta Therapeutics, Inc. (US) | 2019-06-13 | — | — | WO | disclosed |
| EP-1991221-A2 | METHODS FOR INCREASING BLOOD FLOW AND/OR PROMOTING TISSUE REGENERATION | Genzyme Corporation (US) | 2008-11-19 | — | — | EP | disclosed |
| WO-2007106063-A2 | METHODS FOR INCREASING BLOOD FLOW AND/OR PROMOTING TISSUE REGENERATION | GENZYME CORPORATION (US) | 2007-09-20 | — | — | WO | disclosed |