Acrylic Acid Methyl Ester

Acrylic Acid Methyl Ester

SCHEMBL4858706

C=CC(=O)O.C=CC(=O)OC.C=CC(=O)OCO

nearest known ligand 0.47

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.47
ALDH1A1 P00352 6/20 0.42
TP53 P04637 3/20 0.42
HIF1A Q16665 3/20 0.42
CYP3A4 P08684 2/20 0.42
MAPK1 P28482 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 3/20 0.42
HCAR2 Q8TDS4 4/20 0.40
LMNA P02545 1/20 0.40
ALOX15 P16050 2/20 0.36
THRB P10828 2/20 0.36
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
RECQL P46063 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MAPT P10636 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid Methyl Ester SCHEMBL28739620 0.94 TSHR (0.52) TSHRALDH1A1TP53HIF1ACYP3A4
Acrylic Acid SCHEMBL4855025 0.89 TSHR (0.56) TSHRALDH1A1TP53HIF1ACYP3A4
Acrylic Acid Methyl Ester SCHEMBL28739641 0.86 TSHR (0.45) TSHRALDH1A1TP53HIF1ACYP3A4
Acrylic Acid Methyl Ester SCHEMBL28195282 0.85 LMNA (0.56) TSHRALDH1A1TP53HIF1ACYP3A4
Acrylic Acid Methyl Ester SCHEMBL27888603 0.85 LMNA (0.56) TSHRALDH1A1TP53HIF1ACYP3A4
Acrylic Acid Methyl Ester SCHEMBL36950 0.85 LMNA (0.56) TSHRALDH1A1TP53HIF1ACYP3A4
Acrylic Acid Methyl Ester SCHEMBL29169365 0.85 TSHR (0.44) TSHRALDH1A1TP53HIF1ACYP3A4
Acrylic Acid Methyl Ester SCHEMBL4866248 0.85 TSHR (0.70) TSHRALDH1A1TP53HIF1ACYP3A4
Acrylic Acid Ethyl Ester SCHEMBL17848292 0.84 HCAR2 (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
Acrylic Acid Methyl Ester SCHEMBL28739488 0.83 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7399570-B2 Water-soluble negative photoresist polymer and composition containing the same HYNIX SEMICONDUCTOR INC. (KR) 2008-07-15 US disclosed
US-20050282080-A1 Water-soluble negative photoresist polymer and composition containing the same HYNIX SEMICONDUCTOR INC. (KR) 2005-12-22 US disclosed