Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL1162338 | 0.90 | ALDH1A1 (0.32) | — | |
| SCHEMBL366468 | 0.86 | LMNA (0.33) | — | |
| Hydrochloric Acid SCHEMBL28754220 | 0.84 | LMNA (0.32) | — | |
| Hydrochloric Acid SCHEMBL28885497 | 0.84 | LMNA (0.32) | — | |
| Acetic Acid SCHEMBL2414323 | 0.82 | ALDH1A1 (0.34) | — | |
| SCHEMBL11178273 | 0.81 | LMNA (0.32) | — | |
| Ethylene SCHEMBL7526969 | 0.80 | LMNA (0.30) | — | |
| Edetic Acid SCHEMBL2155992 | 0.79 | TDP1 (0.37) | — | |
| SCHEMBL495860 | 0.76 | LMNA (0.36) | — | |
| SCHEMBL9679880 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190055406-A1 | TREATED INORGANIC PARTICULATE MATERIAL FOR IMPROVING PERFORMANCE OF CONSTRUCTION AND ASSEMBLY COMPOUNDS | IMERYS USA, INC. | 2019-02-21 | — | — | US | claimed |
| EP-3328946-A1 | ANTI-SOILING COMPOSITIONS COMPRISING SILICA NANOPATICLES AND FUNCTIONAL SILANE COMPOUNDS AND COATED ARTICLES THEREOF | 3M Innovative Properties Company (US) | 2018-06-06 | — | — | EP | claimed |
| WO-2017015885-A1 | ANTI-SOILING COMPOSITIONS COMPRISING SILICA NANOPATICLES AND FUNCTIONAL SILANE COMPOUNDS AND COATED ARTICLES THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-02-02 | — | — | WO | claimed |
| EP-2943651-A1 | TREATMENT FOR NON-CAKING MINE ROCK DUST | Imerys Pigments, Inc. (US) | 2015-11-18 | — | — | EP | claimed |
| WO-2015054286-A1 | TREATMENTS FOR NON-CAKING MINE ROCK DUST | IMERYS PIGMENTS, INC. (US) | 2015-04-16 | — | — | WO | claimed |
| WO-2014110202-A1 | TREATMENT FOR NON-CAKING MINE ROCK DUST | IMERYS PIGMENTS, INC. (US) | 2014-07-17 | — | — | WO | claimed |
| EP-1838173-B1 | METHOD OF PREVENTING OR REDUCING OFF-FLAVOR IN A BEVERAGE USING SILANE-TREATED SILICA FILTER MEDIA | DOW CORNING (US) | 2013-10-16 | — | — | EP | claimed |
| US-7989010-B2 | Method of reducing off-flavor in a beverage using silane-treated silica filter media | DOW CORNING CORPORATION (US) | 2011-08-02 | — | — | US | claimed |
| US-20090232950-A1 | METHOD OF PREVENTING OR REDUCING OFF-FLAVOR IN A BEVERAGE USING SILANE-TREATED SILICA FILTER MEDIA | DOW CORNING CORPORATION | 2009-09-17 | — | — | US | claimed |
| US-20090214701-A1 | Method of preventing or reducing haze in a beverage using silane-treated silica filter media | DOW CORNING CORPORATION | 2009-08-27 | — | — | US | claimed |
| US-20080185333-A1 | SILANE-TREATED SILICA FILTER MEDIA | DOW CORNING CORPORATION | 2008-08-07 | — | — | US | claimed |
| US-7374684-B2 | Method of separating components in a sample using silane-treated silica filter media | DOW CORNING CORPORATION (US) | 2008-05-20 | — | — | US | claimed |
| US-20070267349-A1 | METHOD OF SEPARATING COMPONENTS IN A SAMPLE USING SILANE-TREATED SILICA FILTER MEDIA | DOW CORNING CORPORATION | 2007-11-22 | — | — | US | claimed |
| EP-1737551-A2 | METHOD OF SEPARATING COMPONENTS IN A SAMPLE USING SILANE-TREATED SILICA FILTER MEDIA | GENENCOR INTERNATIONAL, INC. (US) | 2007-01-03 | — | — | EP | claimed |
| EP-1737305-A2 | METHOD OF PREVENTING OR REDUCING HAZE IN A BEVERAGE USING SILANE-TREATED SILICA FILTER MEDIA | GENENCOR INTERNATIONAL, INC. (US) | 2007-01-03 | — | — | EP | claimed |
| WO-2005117616-A9 | METHOD OF PREVENTING OR REDUCING HAZE IN A BEVERAGE USING SILANE-TREATED SILICA FILTER MEDIA | GENENCOR INT (US) | 2006-05-04 | — | — | WO | claimed |
| WO-2005117616-A2 | METHOD OF PREVENTING OR REDUCING HAZE IN A BEVERAGE USING SILANE-TREATED SILICA FILTER MEDIA | GENENCOR INTERNATIONAL, INC. (US) | 2005-12-15 | — | — | WO | claimed |
| WO-2005115580-A2 | METHOD OF SEPARATING COMPONENTS IN A SAMPLE USING SILANE-TREATED SILICA FILTER MEDIA | GENENCOR INTERNATIONAL, INC. (US) | 2005-12-08 | — | — | WO | claimed |
| US-20050029195-A1 | Method of separating components in a sample using silane-treated silica filter media | DOW CORNING CORPORATION | 2005-02-10 | — | — | US | claimed |
| EP-3377191-B1 | CATIONIC COMPOSITE SILICATE FILTER AIDS | IMERYS FILTRATION MINERALS INC (US) | 2023-05-31 | — | — | EP | disclosed |
| US-11596921-B2 | Cationic composite silicate filter aids | IMERYS USA, INC. (US) | 2023-03-07 | — | — | US | disclosed |
| US-11421531-B2 | Non-caking mine rock dust for use in underground coal mines | IMERYS USA, INC. (US) | 2022-08-23 | — | — | US | disclosed |
| US-11203554-B2 | Anticaking agent for hygroscopic fertilizer | IMERYS USA, INC. (US) | 2021-12-21 | — | — | US | disclosed |
| EP-3289595-B1 | COMPOSITIONS INCLUDING BLENDS OF HYDROPHOBIC AND NON-HYDROPHOBIC INORGANIC PARTICULATE MATERIAL FOR USE IN COVERING PRODUCTS | IMERYS USA INC (US) | 2021-11-24 | — | — | EP | disclosed |
| US-20210301140-A1 | ROCK HARDNESS FOR HYDRAULIC FRACTURING AND ART PRESERVATION | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2021-09-30 | — | — | US | disclosed |
| US-11111786-B2 | Moisture tolerant rock dust and methods of application thereof | IMERYS USA, INC. (US) | 2021-09-07 | — | — | US | disclosed |
| EP-2411329-B1 | NATURAL AMORPHOUS SILICA FILLER PRODUCTS | IMERYS FILTRATION MINERALS INC (US) | 2021-05-19 | — | — | EP | disclosed |
| CN-108026307-B | Controlled polymer foaming by tuning surface interaction between blowing agent and mineral | 英默里斯筛选矿物公司 | 2021-04-13 | — | — | CN | disclosed |
| US-10907022-B2 | Controlled polymer foaming by tuning surface interactions between blowing agents and minerals | IMERYS USA, INC. (US) | 2021-02-02 | — | — | US | disclosed |
| EP-2943651-B1 | TREATMENT FOR NON-CAKING MINE ROCK DUST | IMERYS PIGMENTS INC (US) | 2020-12-30 | — | — | EP | disclosed |
| US-20200181037-A1 | ANTICAKING AGENT FOR HYGROSCOPIC FERTILIZER | IMERYS USA, INC. | 2020-06-11 | — | — | US | disclosed |
| US-20200109629-A1 | NON-CAKING MINE ROCK DUST FOR USE IN UNDERGROUND COAL MINES | IMERYS USA INC (US) | 2020-04-09 | — | — | US | disclosed |
| US-20200048423-A1 | CONTROLLED POLYMER FOAMING BY TUNING SURFACE INTERACTIONS BETWEEN BLOWING AGENTS AND MINERALS | IMERYS USA, INC. | 2020-02-13 | — | — | US | disclosed |
| US-20190055406-A1 | TREATED INORGANIC PARTICULATE MATERIAL FOR IMPROVING PERFORMANCE OF CONSTRUCTION AND ASSEMBLY COMPOUNDS | IMERYS USA, INC. | 2019-02-21 | — | — | US | disclosed |
| US-20180340072-A1 | COMPOSITIONS INCLUDING BLENDS OF HYDROPHOBIC AND NON-HYDROPHOBIC INORGANIC PARTICULATE MATERIAL FOR USE IN COVERING PRODUCTS | IMERYS USA, INC. | 2018-11-29 | — | — | US | disclosed |
| US-20180326395-A1 | CATIONIC COMPOSITE SILICATE FILTER AIDS | IMERYS USA, INC. | 2018-11-15 | — | — | US | disclosed |
| EP-2207416-B1 | ENHANCED RETENTION CAPABILITIES THROUGH METHODS COMPRISING SURFACE TREATMENT OF FUNCTIONAL PARTICULATE CARRIER MATERIALS, AND FUNCTIONAL PARTICULATE CARRIER MATERIALS MADE THEREFROM | IMERYS FILTRATION MINERALS INC (US) | 2018-11-07 | — | — | EP | disclosed |
| EP-3356454-A1 | CONTROLLED POLYMER FOAMING BY TUNING SURFACE INTERACTIONS BETWEEN BLOWING AGENTS AND MINERALS | Imerys Filtration Minerals, Inc. (US) | 2018-08-08 | — | — | EP | disclosed |
| EP-3328946-A1 | ANTI-SOILING COMPOSITIONS COMPRISING SILICA NANOPATICLES AND FUNCTIONAL SILANE COMPOUNDS AND COATED ARTICLES THEREOF | 3M Innovative Properties Company (US) | 2018-06-06 | — | — | EP | disclosed |
| EP-3289595-A1 | COMPOSITIONS INCLUDING BLENDS OF HYDROPHOBIC AND NON-HYDROPHOBIC INORGANIC PARTICULATE MATERIAL FOR USE IN COVERING PRODUCTS | Imerys USA, Inc. (US) | 2018-03-07 | — | — | EP | disclosed |
| US-9834684-B2 | Natural amorphous silica filler products | IMERYS FILTRATION MINERALS, INC. (US) | 2017-12-05 | — | — | US | disclosed |
| US-20170226854-A1 | MOISTURE TOLERANT ROCK DUST AND METHODS OF APPLICATION THEREOF | IMERYS USA, INC. (US) | 2017-08-10 | — | — | US | disclosed |
| US-20170159437-A1 | NON-CAKING MINE ROCK DUST FOR USE IN UNDERGROUND COAL MINES | IMERYS USA, INC. | 2017-06-08 | — | — | US | disclosed |
| EP-3137485-A1 | CHELATOR MODIFIED MAGNETIC SILICA NANOPARTICLES, THEIR USE AND PREPARATION | Universidade de Aveiro (PT) | 2017-03-08 | — | — | EP | disclosed |
| WO-2017015885-A1 | ANTI-SOILING COMPOSITIONS COMPRISING SILICA NANOPATICLES AND FUNCTIONAL SILANE COMPOUNDS AND COATED ARTICLES THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-02-02 | — | — | WO | disclosed |
| WO-2016176134-A1 | COMPOSITIONS INCLUDING BLENDS OF HYDROPHOBIC AND NON-HYDROPHOBIC INORGANIC PARTICULATE MATERIAL FOR USE IN COVERING PRODUCTS | IMERYS PIGMENTS, INC. (US) | 2016-11-03 | — | — | WO | disclosed |
| EP-2943651-A1 | TREATMENT FOR NON-CAKING MINE ROCK DUST | Imerys Pigments, Inc. (US) | 2015-11-18 | — | — | EP | disclosed |
| WO-2015166415-A1 | CHELATOR MODIFIED MAGNETIC SILICA NANOPARTICLES, THEIR USE AND PREPARATION | UNIVERSIDADE DE AVEIRO (PT) | 2015-11-05 | — | — | WO | disclosed |
| WO-2015054286-A1 | TREATMENTS FOR NON-CAKING MINE ROCK DUST | IMERYS PIGMENTS, INC. (US) | 2015-04-16 | — | — | WO | disclosed |
| US-20150037496-A1 | TREATMENTS FOR NON-CAKING MINE ROCK DUST | IMERYS PIGMENTS, INC. | 2015-02-05 | — | — | US | disclosed |
| WO-2014110202-A1 | TREATMENT FOR NON-CAKING MINE ROCK DUST | IMERYS PIGMENTS, INC. (US) | 2014-07-17 | — | — | WO | disclosed |
| EP-2405982-B1 | METHODS FOR REMOVING VICINAL DIOLS FROM LACTIC ACID FERMENTATION BROTH | DOW CORNING (US) | 2013-12-18 | — | — | EP | disclosed |
| EP-1838173-B1 | METHOD OF PREVENTING OR REDUCING OFF-FLAVOR IN A BEVERAGE USING SILANE-TREATED SILICA FILTER MEDIA | DOW CORNING (US) | 2013-10-16 | — | — | EP | disclosed |
| US-8293939-B2 | Methods for removing vicinal diols from lactic acid fermentation broth | DOW CORNING CORPORATION (US) | 2012-10-23 | — | — | US | disclosed |
| US-8263153-B2 | Method of preventing or reducing haze in a beverage using silane-treated silica filter media | DOW CORNING CORPORATION (US) | 2012-09-11 | — | — | US | disclosed |
| US-20120048145-A1 | NATURAL AMORPHOUS SILICA FILLER PRODUCTS | WORLD MINERALS, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| US-20120029231-A1 | METHODS FOR REMOVING VICINAL DIOLS FROM LACTIC ACID FERMENTATION BROTH | DOW CORNING CORPORATION (US) | 2012-02-02 | — | — | US | disclosed |
| EP-2411329-A1 | NATURAL AMORPHOUS SILICA FILLER PRODUCTS | World Minerals, Inc. (US) | 2012-02-01 | — | — | EP | disclosed |
| EP-2405982-A2 | METHODS FOR REMOVING VICINAL DIOLS FROM LACTIC ACID FERMENTATION BROTH | Dow Corning Corporation (US) | 2012-01-18 | — | — | EP | disclosed |
| US-7989010-B2 | Method of reducing off-flavor in a beverage using silane-treated silica filter media | DOW CORNING CORPORATION (US) | 2011-08-02 | — | — | US | disclosed |
| US-7850012-B2 | Silane-treated silica filter media | DOW CORNING CORPORATION (US) | 2010-12-14 | — | — | US | disclosed |
| US-20100239679-A1 | ENHANCED RETENTION CAPABILITIES THROUGH METHODS COMPRISING SURFACE TREATMENT OF FUNCTIONAL PARTICULATE CARRIER MATERIALS, AND FUNCTIONAL PARTICULATE CARRIER MATERIALS MADE THEREFROM | WORLD MINERALS, INC. (US) | 2010-09-23 | — | — | US | disclosed |
| WO-2010104677-A2 | METHODS FOR REMOVING VICINAL DIOLS FROM LACTIC ACID FERMENTATION BROTH | DOW CORNING CORPORATION (US) | 2010-09-16 | — | — | WO | disclosed |
| WO-2010104831-A1 | NATURAL AMORPHOUS SILICA FILLER PRODUCTS | WORLD MINERALS, INC. (US) | 2010-09-16 | — | — | WO | disclosed |
| US-20090232950-A1 | METHOD OF PREVENTING OR REDUCING OFF-FLAVOR IN A BEVERAGE USING SILANE-TREATED SILICA FILTER MEDIA | DOW CORNING CORPORATION | 2009-09-17 | — | — | US | disclosed |
| US-20090214701-A1 | Method of preventing or reducing haze in a beverage using silane-treated silica filter media | DOW CORNING CORPORATION | 2009-08-27 | — | — | US | disclosed |
| US-20090030222-A1 | SYSTEMS AND METHODS FOR FUNCTIONALIZING PARTICULATES WITH SILANE-CONTAINING MATERIALS | DOW CORNING CORPORATION | 2009-01-29 | — | — | US | disclosed |
| US-20080185333-A1 | SILANE-TREATED SILICA FILTER MEDIA | DOW CORNING CORPORATION | 2008-08-07 | — | — | US | disclosed |
| US-7374684-B2 | Method of separating components in a sample using silane-treated silica filter media | DOW CORNING CORPORATION (US) | 2008-05-20 | — | — | US | disclosed |
| US-20070267349-A1 | METHOD OF SEPARATING COMPONENTS IN A SAMPLE USING SILANE-TREATED SILICA FILTER MEDIA | DOW CORNING CORPORATION | 2007-11-22 | — | — | US | disclosed |
| EP-1838173-A2 | METHOD OF PREVENTING OR REDUCING OFF-FLAVOR IN A BEVERAGE USING SILANE-TREATED SILICA FILTER MEDIA | DOW CORNING CORPORATION (US) | 2007-10-03 | — | — | EP | disclosed |
| US-7264728-B2 | Method of separating components in a sample using silane-treated silica filter media | DOW CORNING CORPORATION (US) | 2007-09-04 | — | — | US | disclosed |
| EP-1737551-A2 | METHOD OF SEPARATING COMPONENTS IN A SAMPLE USING SILANE-TREATED SILICA FILTER MEDIA | GENENCOR INTERNATIONAL, INC. (US) | 2007-01-03 | — | — | EP | disclosed |
| EP-1737305-A2 | METHOD OF PREVENTING OR REDUCING HAZE IN A BEVERAGE USING SILANE-TREATED SILICA FILTER MEDIA | GENENCOR INTERNATIONAL, INC. (US) | 2007-01-03 | — | — | EP | disclosed |
| WO-2006065556-A2 | METHOD OF PREVENTING OR REDUCING OFF-FLAVOR IN A BEVERAGE USING SILANE-TREATED SILICA FILTER MEDIA | DOW CORNING CORPORATION (US) | 2006-06-22 | — | — | WO | disclosed |
| WO-2005117616-A9 | METHOD OF PREVENTING OR REDUCING HAZE IN A BEVERAGE USING SILANE-TREATED SILICA FILTER MEDIA | GENENCOR INT (US) | 2006-05-04 | — | — | WO | disclosed |
| WO-2005117616-A2 | METHOD OF PREVENTING OR REDUCING HAZE IN A BEVERAGE USING SILANE-TREATED SILICA FILTER MEDIA | GENENCOR INTERNATIONAL, INC. (US) | 2005-12-15 | — | — | WO | disclosed |
| WO-2005115580-A2 | METHOD OF SEPARATING COMPONENTS IN A SAMPLE USING SILANE-TREATED SILICA FILTER MEDIA | GENENCOR INTERNATIONAL, INC. (US) | 2005-12-08 | — | — | WO | disclosed |
| EP-1545734-A1 | METHOD OF SEPARATING COMPONENTS IN A SAMPLE USING SILANE-TREATED SILICA FILTER MEDIA | DOW CORNING CORPORATION (US) | 2005-06-29 | — | — | EP | disclosed |
| US-20050029195-A1 | Method of separating components in a sample using silane-treated silica filter media | DOW CORNING CORPORATION | 2005-02-10 | — | — | US | disclosed |
| US-20040211724-A1 | Method of separating components in a sample using silane-treated silica filter media | DOW CORNING CORPORATION | 2004-10-28 | — | — | US | disclosed |
| WO-2004041401-A1 | METHOD OF SEPARATING COMPONENTS IN A SAMPLE USING SILANE-TREATED SILICA FILTER MEDIA | DOW CORNING CORPORATION (US) | 2004-05-21 | — | — | WO | disclosed |
| WO-2004041401-A1 | METHOD OF SEPARATING COMPONENTS IN A SAMPLE USING SILANE-TREATED SILICA FILTER MEDIA | DOW CORNING CORPORATION (US) | 2004-05-21 | — | — | WO | disclosed |